The Feasibility of Large Conization as a Fertility-Sparing Treatment in Young Women with Early-Stage Cervical Cancer

2022 ◽  
Author(s):  
Mohamed Laban ◽  
Seif Tarek El-Swaify ◽  
Nourhan Farrag
Keyword(s):  
Cervical Cancer ◽  
Young Women ◽  
Early Stage ◽  
Fertility Sparing ◽  
Early Stage Cervical Cancer

scholarly journals Trends in Use and Survival Associated With Fertility-Sparing Trachelectomy for Young Women With Early-Stage Cervical Cancer

2018 ◽  
Vol 131 (6) ◽  
pp. 1085-1094 ◽  
Author(s):  
Rosa R. Cui ◽  
Ling Chen ◽  
Ana I. Tergas ◽  
June Y. Hou ◽  
Caryn M. St. Clair ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Young Women ◽  
Early Stage ◽  
Fertility Sparing ◽  
Early Stage Cervical Cancer

scholarly journals Large Conization—Retrospective Monocentric Results for Fertility Preservation in Young Women with Early Stage Cervical Cancer

2021 ◽  
Author(s):  
Christos Tsaousidis ◽  
Bernhard Kraemer ◽  
Stefan Kommoss ◽  
Andreas Hartkopf ◽  
Sara Brucker ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Young Women ◽  
Early Stage ◽  
Resection Margins ◽  
Obstetric Outcomes ◽  
Safe Alternative ◽  
Fertility Sparing ◽  
Early Stage Cervical Cancer ◽  
Cervical Segment ◽  
Associated Risk Factors

Abstract  The shorter cervical segment after classic radical trachelectomy (RT) imposes a number of pregnancy associated risk factors. In this aspect, large conization (LC) could be an oncologically safe alternative to RT in young women with early stage cervical cancer who want to spare their fertility. Our aim was to evaluate fertility-sparing surgical treatment of early stage cervical cancer after the introduction of LC. Our objectives were to assess surgical, oncological, fertility and obstetric outcomes. We retrospectively investigated oncological and fertility outcomes of patients who underwent LC in a large oncological single University centre between 2009 and 2014. Medical records were reviewed and analysed for surgical, oncological, fertility and obstetric outcomes. Postal questionnaires were collected to further evaluate and validate the fertility and obstetric outcomes. A total of 23 LCs were analysed. Seven patients had to undergo secondary radical hysterectomy after LC due to unclear resection margins. Nine of 16 women tried to conceive, of which all nine became pregnant. Seven patients underwent a prophylactic cerclage between 13 and 16 gestational weeks and seven women delivered 9 children; the majority of women conceived spontaneously. Follow-up time was a median of 3.9 years (2.6–8 years). There was no relapse of cervical cancer in the investigated timeframe. Early stage cervical cancers treated by LC are associated with excellent oncological outcomes. LC appears to be a safe option for eligible women who intend to maintain their fertility.

scholarly journals Fertility-sparing surgery for young women with early-stage cervical cancer

2011 ◽  
Vol 118 (3) ◽  
pp. 377-378 ◽  
Author(s):  
JR Smith ◽  
S Ghaem-Maghami ◽  
A McIndoe ◽  
A Farthing ◽  
P Mason ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Young Women ◽  
Early Stage ◽  
Fertility Sparing Surgery ◽  
Fertility Sparing ◽  
Early Stage Cervical Cancer

Outcomes of Fertility-Sparing Radical Trachelectomy in Early-Stage Cervical Cancer

2010 ◽  
Vol 17 (6) ◽  
pp. S6
Author(s):  
M.K. Kim ◽  
C.H. Choi ◽  
T. Song ◽  
H.S. Park ◽  
Y-Y. Lee ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Early Stage ◽  
Radical Trachelectomy ◽  
Fertility Sparing ◽  
Early Stage Cervical Cancer
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