Increase in S-wave amplitude during ischemic ST-segment depression in stable angina pectoris

1987 ◽  
Vol 59 (15) ◽  
pp. 1295-1299 ◽  
Author(s):  
James J. Glazier ◽  
Sergio Chierchia ◽  
Alberto Margonato ◽  
Attilio Maseri
Keyword(s):  
Angina Pectoris ◽  
Stable Angina ◽  
Wave Amplitude ◽  
Stable Angina Pectoris ◽  
S Wave ◽  
St Segment

Chronic Stable Angina: Comparison of Verapamil and Propranolol

1982 ◽  
Vol 10 (5) ◽  
pp. 361-366 ◽  
Author(s):  
E Southall ◽  
N R Nutt ◽  
R D Thomas
Keyword(s):  
Angina Pectoris ◽  
Exercise Testing ◽  
Stable Angina ◽  
Crossover Trial ◽  
Chronic Stable Angina ◽  
Stable Angina Pectoris ◽  
Double Blind ◽  
Exercise Time ◽  
Electrocardiographic Monitoring ◽  
St Segment

The effect of verapamil 120 mg t.d.s. was compared with propranolol 160 mg b.d. in the treatment of stable angina pectoris. Nineteen patients were studied in a randomized, double-blind, crossover trial, using patient diaries, exercise-testing and ambulatory electrocardiographic monitoring. Both drugs were given for 1 month. On average the number of attacks of angina was reduced equally by verapamil and propranolol. The degree of electrocardiographic evidence of myocardial ischaemia was decreased by the same amount, but verapamil was significantly more effective in prolonging the exercise time. Both drugs reduced the number of episodes of ST-segment depression during 24 hours of ambulatory electrocardiographic monitoring, which was analyzed in nine patients. It is concluded that verapamil compares very favourably with propranolol in the treatment of stable angina, and is more beneficial in improving exercise capacity.

Mechanisms of arrhythmias accompanying ST-segment depression on ambulatory monitoring in stable angina pectoris

1987 ◽  
Vol 60 (16) ◽  
pp. 1246-1253 ◽  
Author(s):  
Gian Piero Carboni ◽  
Avijit Lahiri ◽  
Peter M.M. Cashman ◽  
Edward B. Raftery
Keyword(s):  
Angina Pectoris ◽  
Stable Angina ◽  
Ambulatory Monitoring ◽  
Stable Angina Pectoris ◽  
St Segment

scholarly journals Efficacy and safety of oral Guanxinshutong capsules in patients with stable angina pectoris in China: a prospective, multicenter, double-blind, placebo-controlled, randomized clinical trial

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Yang Li ◽  
Lei Zhang ◽  
Shuzheng Lv ◽  
Xiaozeng Wang ◽  
Jian Zhang ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Placebo Group ◽  
Angina Pectoris ◽  
Randomized Clinical Trial ◽  
Stable Angina ◽  
Efficacy And Safety ◽  
Stable Angina Pectoris ◽  
Double Blind ◽  
Double Blind Placebo ◽  
St Segment

Abstract Background To assess the efficacy and safety of oral Guanxinshutong (GXST) capsules in Chinese patients with stable angina pectoris (SAP) in a prospective, multicenter, double-Blind, placebo-controlled, randomized clinical trial (clinicaltrials.gov Identifier: NCT02280850). Methods Eligible patients were randomized 1:1 to the GXST or placebo group. Current standard antianginal treatment except for nitrate drugs was continued in both groups, who received an additional 4-week treatment of GXST capsule or placebo. Primary endpoint was the change from baseline in angina attack frequency after the 4-week treatment. Secondary endpoints included the reduction of nitroglycerin dose, score of Seatntle Agina Questionnaire, exercise tolerance test defined as time to onset of chest pain and ST-segment depression at least 1 mm greater than the resting one. Results A total of 300 SAP patients from 12 centers in China were enrolled between January 2013 and October 2015, and they were randomly divided into the GXST group and the placebo group (150 patients in each group). Of whom, 287 patients completed the study (143 patients in the GXST group, 144 patients in the placebo group). The baseline characteristics of the two groups were comparable. After 4-week treatment with GXST capsules, the number of angina attacks and the consumption of short-acting nitrates were significantly reduced. In addition, the quality of life of patients were also substantially improved in the GXST group. No significant differences in the time of onset of angina and 1-mm ST segment depression were noted between the two groups. 7 patients (4.1%) in the GXST group and 3 patients (2.1%) in the placebo group reported at least one adverse event, respectively. Conclusions GXST capsules are beneficial for the treatment of SAP patients.

Frequency of ST-segment depression produced by mental stress in stable angina pectoris from coronary artery disease

1988 ◽  
Vol 61 (13) ◽  
pp. 989-993 ◽  
Author(s):  
Joan Barry ◽  
Andrew P. Selwyn ◽  
Elizabeth G. Nabel ◽  
Michael B. Rocco ◽  
Kimberely Mead ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Angina Pectoris ◽  
Stable Angina ◽  
Mental Stress ◽  
Stable Angina Pectoris ◽  
St Segment ◽  
Artery Disease
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