Affinity capillary electrophoresis applied to the studies of interactions of a member of heat shock protein family with an immunosuppressant

1994 ◽  
Vol 680 (2) ◽  
pp. 395-403 ◽  
Author(s):  
Jinping Liu ◽  
Kevin J. Volk ◽  
Mike S. Lee ◽  
Edward H. Kerns ◽  
Ira E. Rosenberg
Keyword(s):  
Capillary Electrophoresis ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Protein Family ◽  
Affinity Capillary Electrophoresis

The 70kDa Heat Shock Protein Family and Learning

2009 ◽  
pp. 217-240
Author(s):  
Martine Ammassari-Teule ◽  
Giuseppina Mariucci ◽  
Maria Vittoria Ambrosini
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Protein Family

scholarly journals Role of the heat shock protein family in bone metabolism

2018 ◽  
Vol 23 (6) ◽  
pp. 1153-1164 ◽  
Author(s):  
Kai Hang ◽  
Chenyi Ye ◽  
Erman Chen ◽  
Wei Zhang ◽  
Deting Xue ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Bone Metabolism ◽  
Protein Family

scholarly journals Increased Reticulon 3 (RTN3) Leads to Obesity and Hypertriglyceridemia by Interacting With Heat Shock Protein Family A (Hsp70) Member 5 (HSPA5)

Circulation ◽  
2018 ◽  
Vol 138 (17) ◽  
pp. 1828-1838 ◽  
Author(s):  
Rong Xiang ◽  
Liang-liang Fan ◽  
Hao Huang ◽  
Ya-qin Chen ◽  
Wanxia He ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Protein Family

Differential increase in the expression of heat shock protein family members during sleep deprivation and during sleep

Neuroscience ◽  
2003 ◽  
Vol 116 (1) ◽  
pp. 187-200 ◽  
Author(s):  
A. Terao ◽  
T.L. Steininger ◽  
K. Hyder ◽  
A. Apte-Deshpande ◽  
J. Ding ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Sleep Deprivation ◽  
Family Members ◽  
Protein Family ◽  
Differential Increase

Expression of the small heat shock protein family in the mouse CNS: Differential anatomical and biochemical compartmentalization

Neuroscience ◽  
2008 ◽  
Vol 153 (2) ◽  
pp. 483-491 ◽  
Author(s):  
S. Quraishe ◽  
A. Asuni ◽  
W.C. Boelens ◽  
V. O'Connor ◽  
A. Wyttenbach
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Small Heat Shock Protein ◽  
Protein Family

scholarly journals Downregulation of the constitutively expressed Hsc70 in diabetic myocardium is mediated by insulin deficiency

2006 ◽  
Vol 190 (2) ◽  
pp. 433-440 ◽  
Author(s):  
Harn-Shen Chen ◽  
Jia Jia ◽  
Hou-Fen Su ◽  
Hong-Da Lin ◽  
Jaw-Wen Chen ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Cardiac Muscle ◽  
Streptozotocin Diabetes ◽  
Protein Family ◽  
Insulin Deficiency ◽  
Cardiac Muscle Cells ◽  
Diabetic Myocardium

The 70 kDa heat shock protein family plays important cardiac protective roles against myocardial injuries. Reduced myocardial protection is a common feature of diabetic myocardium. This study was carried out to define the changes in the 70 kDa heat shock protein family in the myocardium in the of streptozotocin-diabetes rats, and to explore the mechanisms through which diabetes alters the abundance of Hsp70/Hsc70 in cardiac muscle. In the diabetic myocardium, the abundance of Hsc70 was significantly reduced. The abundance of Hsp70 was low in cardiac muscle and was not induced in the diabetic myocardium. Unlike Hsp60, Hsp70 and Hsc70 did not augment insulin-like growth factor-I receptor signaling in cardiac muscle cells. In cultured cardiomyocytes, insulin directly increased the abundance of Hsc70, whereas insulin could not modulate Hsp70. Treating diabetic rats with insulin restored myocardial Hsc70 level, but phlorizin treatment failed to restore myocardial Hsc70. These in vivo and in vitro studies showed that downregulation of Hsc70 in diabetic myocardium was secondary to insulin deficiency. Thus, insulin played a major role in maintaining adequate expression of Hsc70 in cardiac muscle.

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