The urine cyclic AMP response to parathyroid extract (PTE) administration in normal subjects and patients with parathyroid dysfunction

Metabolism ◽  
1979 ◽  
Vol 28 (8) ◽  
pp. 814-819 ◽  
Author(s):  
J.R. Tucci ◽  
R.S. Perlstein ◽  
L.E. Kopp
Keyword(s):  
Cyclic Amp ◽  
Normal Subjects ◽  
Parathyroid Extract ◽  
Parathyroid Dysfunction

Urinary and nephrogenous cyclic AMP and renal phosphate handling in normal subjects and patients with parathyroid dysfunction

1984 ◽  
Vol 106 (2) ◽  
pp. 219-226
Author(s):  
S. Khoury ◽  
J. R. Tucci
Keyword(s):  
Cyclic Amp ◽  
Primary Hyperparathyroidism ◽  
Normal Subjects ◽  
Normal Group ◽  
Permanent Hypoparathyroidism ◽  
Urinary Cyclic Amp ◽  
Parathyroid Dysfunction

Abstract. Studies were performed in 60 patients with proven primary hyperparathyroidism pre-operatively and in 54 of these patients post-operatively, 22 patients with permanent hypoparathyroidism and 34 normal subjects. Urinary and nephrogenous cyclic AMP excretion were increased in the hyperparathyroid patients with an overlap of values with the normal group of 10 and 9%, respectively. Values fell in all patients post-operatively, and were decreased in those with permanent hypoparathyroidism. TmPO4/GFR was decreased in the preoperative hyperparathyroid patients and rose postoperatively while it was increased in the hypoparathyroid patients with an overlap of values with the normal group of 9%. Post-operative hypocalcaemia due to bone hunger was associated with continuing normo- or hypophosphataemia and urinary cyclic AMP that exceeded 4.5 nm/dl GF while those who developed permanent hypoparathyroidism had hyperphosphataemia, increased TmPO4/GFR and urinary cyclic AMP that was less than 3.5 nM/dl G.F. Urinary and nephrogenous cyclic AMP were equally effective in characterizing patients with primary hyperparathyroidism and less effective in distinguishing patients with hypoparathyroidism from normal while TmPO4/GFR estimates were more effective in delineating the hypoparathyroid state.

scholarly journals Plasma cyclic nucleotide levels in acute leukemia patients

Blood ◽  
1987 ◽  
Vol 69 (6) ◽  
pp. 1613-1616 ◽  
Author(s):  
M Peracchi ◽  
V Toschi ◽  
F Bamonti-Catena ◽  
L Lombardi ◽  
B Bareggi ◽  
...  
Keyword(s):  
Complete Remission ◽  
Cyclic Amp ◽  
Acute Leukemia ◽  
Cyclic Nucleotide ◽  
Normal Subjects ◽  
Response To Treatment ◽  
Active Stage ◽  
Normal Range ◽  
Plasma Camp ◽  
Camp Levels

Abstract To verify the clinical usefulness of extracellular cyclic nucleotide determination as a tumor marker, plasma cyclic AMP (cAMP) and cyclic GMP (cGMP) levels were measured in 70 normal subjects and 173 acute leukemia patients studied in different stages of their disease. Mean plasma cAMP levels were similar in leukemic and normal subjects, although in 48 patients in the active stage of the disease, first diagnosis, or relapse, the cAMP values were below the normal range, and most of these patients failed to respond to chemotherapy. Plasma cGMP levels were markedly elevated in untreated patients, normalized in all patients who attained complete remission, and increased promptly to pretreatment values in patients who relapsed, suggesting that their determination may be useful to monitor the patients' response to treatment.

Effect of Parathyroid Extract on Renal Cyclic AMP Excretion in Patients with Normocalciuric Nephrolithiasis

1978 ◽  
Vol 10 (02) ◽  
pp. 158-161 ◽  
Author(s):  
H. Lilienfeld-Toal ◽  
K. Mackes ◽  
U. Klehr ◽  
H. Dengler
Keyword(s):  
Cyclic Amp ◽  
Parathyroid Extract

scholarly journals 1,25-Dihydroxyvitamin D production stimulated by dibutyryl 3',5'-cyclic AMP in normal subjects and a patient with pseudohypoparathyroidism.

1982 ◽  
Vol 138 (4) ◽  
pp. 411-418
Author(s):  
HIROSHI UNAKAMI ◽  
YOHTARO FURUKAWA ◽  
HYO EUY SOHN ◽  
SHIGERU YUMITA ◽  
RYO MIURA ◽  
...  
Keyword(s):  
Cyclic Amp ◽  
Normal Subjects ◽  
Dihydroxyvitamin D ◽  
1,25 Dihydroxyvitamin D

The Role of Parathyroid Hormone in the Gastro-Intestinal Absorption of Calcium

1970 ◽  
Vol 39 (1) ◽  
pp. 89-94 ◽  
Author(s):  
M. R. Wills ◽  
J. Wortsman ◽  
C. Y. C. Pak ◽  
F. C. Bartter
Keyword(s):  
Parathyroid Hormone ◽  
Intestinal Absorption ◽  
Calcium Absorption ◽  
Control Period ◽  
Normal Subjects ◽  
Parathyroid Extract

1. Gastrointestinal calcium absorption was studied in six normal subjects and in one patient with idiopathic hypoparathyroidism during a control period and during treatment with parathyroid extract. 2. In all subjects there was a small increase in the gastro-intestinal absorption of calcium during the administration of parathyroid extract.

Urinary Adenosine Cyclic 3′,5′-Monophosphate in Idiopathic Calcium Stone-Formers: Response to An Oral Calcium Load

1984 ◽  
Vol 66 (2) ◽  
pp. 193-199 ◽  
Author(s):  
V. R. Walker ◽  
R. A. L. Sutton
Keyword(s):  
Cyclic Amp ◽  
Excretion Rate ◽  
Normal Subjects ◽  
Oral Calcium ◽  
Calcium Stone ◽  
Stone Formers ◽  
Glomerular Filtrate ◽  
Calcium Load ◽  
Urinary Cyclic Amp ◽  
Lower Urinary

1. Idiopathic calcium stone-formers with hypercalciuria during fasting have significantly lower urinary cyclic AMP levels (nmol/dl of glomerular filtrate) than fasting normocalciuric stone-formers. 2. Female subjects, including both normal subjects and idiopathic calcium stone-formers, have higher urinary cyclic AMP levels than their male counterparts, and this difference is significant when urinary cyclic AMP is expressed in the units μmol/g of creatinine. Expressing urinary cyclic AMP in nmol/dl of glomerular filtrate reduces this difference but does not abolish it. Thus, in comparing urinary cyclic AMP levels in various subgroups of the calcium stone-formers and in normal subjects, both sex differences and the units of urinary cyclic AMP expression must be taken into consideration. 3. The magnitude of the change in urinary cyclic AMP in response to an oral calcium load appears to depend on the antecedent urinary cyclic AMP excretion rate, whereby those individuals (either normal subjects or calcium stone-formers) having the highest urinary cyclic AMP levels demonstrate the greatest fall in urinary cyclic AMP after a calcium load.

Sign in / Sign up

Export Citation Format

Share Document