Anaplastic astrocytoma with granular cell differentiation: Case report and review of the literature

1993 ◽  
Vol 24 (7) ◽  
pp. 805-808 ◽  
Author(s):  
Mark J. Melaragno ◽  
Richard A. Prayson ◽  
Michael A. Murphy ◽  
Samuel J. Hassenbusch ◽  
Melinda L. Estes
2018 ◽  
Vol 30 (6) ◽  
pp. 951-954 ◽  
Author(s):  
Pompei Bolfa ◽  
Lusan DellaGrotte ◽  
Teri Weronko ◽  
Anibal G. Armien

We report a case of cutaneous epithelioid hemangiosarcoma in a dog in which the majority of the neoplastic cells displayed histologic and ultrastructural features similar to those seen in granular cell tumors (GCTs). This intersection of hemangiosarcoma and granular cell change adds to the argument that GCTs are heterogeneous in histologic origin and underlines the fact that pathologists should not consider all GCTs as a single entity. The combination of histology in typical areas of the tumor with ultrastructural changes and the correct immunohistochemical markers can facilitate the accurate diagnosis of tumors with granular cell differentiation. Besides characteristic intracytoplasmic PAS-positive granules and ultrastructural proteinaceous accumulation within single membrane vesicles (presumably lysosomes and phagolysosomes), we suggest the following combination of markers for the diagnosis of granular cell angiosarcoma and/or hemangiosarcoma: vimentin positive, NSE and/or S100 negative, CD31 positive. We propose that the histologic granular appearance represents a metabolic defect of the neoplastic cells, which supports variability in cell origin for granular cell differentiation.


2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Ramin Niknam ◽  
Kamran Bagheri Lankarani ◽  
Bita Geramizadeh

Gastrointestinal granular cell tumors are uncommon. The most common site of gastrointestinal granular cell tumor (GCT) is esophagus. We report a case of esophageal GCT incidentally diagnosed by endoscopy. The lesion was evaluated by endoscopic ultrasonography and resected using the endoscopic technique without complication.


Neurosurgery ◽  
1998 ◽  
Vol 42 (1) ◽  
pp. 166-170 ◽  
Author(s):  
Bernhard Schaller ◽  
Eberhard Kirsch ◽  
Markus Tolnay ◽  
Thomas Mindermann

1983 ◽  
Vol 14 (2) ◽  
pp. 125-129
Author(s):  
Zeynel A Karcioglu ◽  
Gregory L Hemphill ◽  
Brandon M Wool

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Preston Gardner ◽  
Arlene Rozzelle

Congenital granular cell tumors are infrequently occurring masses occurring on a neonate’s gingiva/alveolus. These lesions are benign with no noted malignant transformation, and treatment of excision is based on its effect on the neonate’s respiratory ability and/or nutritional intake. The purpose of this review is to discuss a case of a congenital granular cell tumor and its treatment and review of the literature including demographics, histopathology, and operative treatment.


2000 ◽  
Vol 4 (4) ◽  
pp. 245-251 ◽  
Author(s):  
Abdul M. Al-Ghamdi ◽  
Julia D.A. Flint ◽  
Nestor L. Muller ◽  
Ken C. Stewart

2010 ◽  
Vol 37 (3) ◽  
pp. 380-385 ◽  
Author(s):  
Natalie A. Wright ◽  
Crystal G. Thomas ◽  
Antoanella Calame ◽  
Clay J. Cockerell

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