Congenital Granular Cell Tumor: Case Report and Review

Congenital granular cell tumors are infrequently occurring masses occurring on a neonate’s gingiva/alveolus. These lesions are benign with no noted malignant transformation, and treatment of excision is based on its effect on the neonate’s respiratory ability and/or nutritional intake. The purpose of this review is to discuss a case of a congenital granular cell tumor and its treatment and review of the literature including demographics, histopathology, and operative treatment.

Neumann’s Tumor - A Rare Neonatal Tumor

Neumann’s tumor, also known as congenital granular cell tumor, congenital myoblastoma, congenital epulis, was first described by Neumann in 1871. It’s a rare cause of newborn’s intraoral masses. they are usually on the maxilla and soliter , they can rarely be seen on the mandibula and multiple. Even if it is not clinically symptomatic, surgical resection is performed because of its cosmetic appearance, negative psychological effect on the family , differential diagnosis and treatment. Neumann’s tumor is fully cured by surgical resection because it does not show recurrence or metastasis after excision.

Multiple Congenital Granular Cell Tumor in a Neonate - A Rare Case

Congenital granular cell tumor (CGCT) is an uncommon congenital benign epulis in neonates. A preliminary diagnosis is usually put forth clinically but may be confused with other anomalies. Herein, we report an unusual case of intra oral congenital granular cell tumor in a 4-day-old female newborn. The tumor was excised completely. At 3-month follow-up, the baby is doing fine without any recurrence.

Congenital Granular Cell Tumor – A Rare Entity

Congenital granular cell tumor is a rare benign neoplastic growth affecting the gingival mucosa of neonates. Prenatal ultrasound diagnosis has recently come to focus and in spite of several reports on immune-histochemical and other advanced marker studies, the cause and origin of the lesion remains debatable till date. Review of literature on prenatal diagnosis and histopathology along with immunohistochemistry is discussed.

Congenital granular cell tumor in newborn

ABSTRACTThe congenital granular cell tumor (CGCT) is quite scarce at the infant. The patient, who has a 2-day-old female newborn, was admitted to the Department of Pediatric Dentistry. Baby had a smooth surfaced, non-fixated mass, found on the anterior part of the mandibular alveole, developing from the gingival mucosa. Clinical examination showed a 1 cm Χ 1 cm Χ 1.8 cm pedunculated, regular, pink colorful soft-tissue gob on the alveolar crest to the left side of the mandible. The gob was removed on the seventh postnatal day under general anesthesia. Then, the specimen was evaluated histopathologically. Post-operative recovery and surgical site healing was satisfactory. The CGCT is a rare, degenerative or reactive lesion of the oral cavity. The mass may surgically remove if the diagnosis is not definite clinically and this can lead therapeutic effect.