Influence of cations on basic and neutral amino acid uptake by human placental villi

Placenta ◽  
1994 ◽  
Vol 15 (7) ◽  
pp. A39
Author(s):  
Roy B. Krishna ◽  
Joseph Dancis ◽  
Mortimer Levitz
Keyword(s):  
Amino Acid ◽  
Amino Acid Uptake ◽  
Neutral Amino Acid ◽  
Acid Uptake ◽  
Placental Villi

Seasonal variation in glucose and neutral amino acid uptake in the estuarine crab Neohelice granulata

2009 ◽  
Vol 153 (3) ◽  
pp. 252-257 ◽  
Author(s):  
Sandra Costa Valle ◽  
Paula Eichler ◽  
José Eduardo Maciel ◽  
Gabriel Machado ◽  
Luiz Carlos Kucharski ◽  
...  
Keyword(s):  
Seasonal Variation ◽  
Amino Acid ◽  
Amino Acid Uptake ◽  
Neutral Amino Acid ◽  
Acid Uptake ◽  
Neohelice Granulata

Vasoactive Intestinal Peptide induces glucose and neutral amino acid uptake through mTOR pathways in human trophoblast cells

Placenta ◽  
2019 ◽  
Vol 83 ◽  
pp. e60-e61
Author(s):  
Fatima Merech ◽  
Elizabeth Soczewski ◽  
Vanesa Hauk ◽  
Daniel Paparini ◽  
Rosanna Ramhorst ◽  
...  
Keyword(s):  
Amino Acid ◽  
Vasoactive Intestinal Peptide ◽  
Amino Acid Uptake ◽  
Neutral Amino Acid ◽  
Acid Uptake ◽  
Trophoblast Cells ◽  
Human Trophoblast ◽  
Human Trophoblast Cells

Effect of hyper or hypo-osmotic conditions on neutral amino acid uptake and oxidation in tissues of the crab Chasmagnathus granulata

2005 ◽  
Vol 140 (4) ◽  
pp. 561-567 ◽  
Author(s):  
Vanessa Schein ◽  
Ana Lúcia Fernandes Chittó ◽  
Rodrigo Etges ◽  
Luiz Carlos Kucharski ◽  
Alain van Wormhoudt ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Uptake ◽  
Neutral Amino Acid ◽  
Acid Uptake ◽  
Chasmagnathus Granulata ◽  
Crab Chasmagnathus Granulata

ASC system activity is altered by development of cell polarity in trophoblast from human placenta

1993 ◽  
Vol 265 (1) ◽  
pp. C212-C217 ◽  
Author(s):  
T. C. Furesz ◽  
C. H. Smith ◽  
A. J. Moe
Keyword(s):  
Amino Acid ◽  
Primary Cultures ◽  
Amino Acid Uptake ◽  
Selective Inhibition ◽  
Isobutyric Acid ◽  
Neutral Amino Acid ◽  
Transport Systems ◽  
Bewo Cell ◽  
Acid Uptake

Pathways of neutral amino acid uptake were investigated in vitro during differentiation of primary cultures of trophoblast isolated from full-term human placentas and a clone (b30) of the BeWo cell line. Inhibition of initial alanine (0.1 microM) uptake by 2-(methylamino)isobutyric acid and unlabeled alanine revealed two Na(+)-dependent systems and one Na(+)-independent transporter. Characterization of these transporters, by selective inhibition, suggested system A, ASC, and L-like transporters. Concomitant with formation of microvillous membrane and syncytium, system ASC activity decreased from 16.1 +/- 2.8 pmol.mg DNA-1.min-1 at 24 h to 2.4 +/- 1.1 pmol.mg DNA-1.min-1 at 72 h. Na(+)-independent alanine uptake increased from 6.0 +/- 2.0 to 12.9 +/- 0.9 pmol.mg DNA-1.min-1 at 24 and 72 h, respectively. Similarly, alpha-(methylamino)isobutyric acid-insensitive, Na(+)-dependent activity in b30 cells (100 microM alanine) decreased from 6.5 +/- 1.6 to 1.2 +/- 1.2 nmol.mg DNA-1.min-1 for control and forskolin-treated cells, respectively. We conclude that membrane specialization accompanying fusion and differentiation of the cytotrophoblast to form syncytiotrophoblast results in a polarization of neutral amino acid transport systems.

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