Identification of an Fc receptor for IgG1 and IgG2 on guinea-pig polymorphonuclear leukocytes

1987 ◽  
Vol 24 (8) ◽  
pp. 831-837 ◽  
Author(s):  
N TOHORU ◽  
T KOICHI ◽  
M JYUNICHI ◽  
S HIDEKI ◽  
S TOSHIRO ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Polymorphonuclear Leukocytes ◽  
Fc Receptor

scholarly journals Arachidonate 5-lipoxygenase of guinea pig peritoneal polymorphonuclear leukocytes. Activation by adenosine 5'-triphosphate.

1983 ◽  
Vol 258 (9) ◽  
pp. 5754-5758
Author(s):  
K Ochi ◽  
T Yoshimoto ◽  
S Yamamoto ◽  
K Taniguchi ◽  
T Miyamoto
Keyword(s):  
Guinea Pig ◽  
Polymorphonuclear Leukocytes

scholarly journals Intracellular localization of Rickettsia tsutsugamushi in polymorphonuclear leukocytes.

1979 ◽  
Vol 150 (3) ◽  
pp. 703-708 ◽  
Author(s):  
Y Rikihisa ◽  
S Ito
Keyword(s):  
Guinea Pig ◽  
Cell Cultures ◽  
Polymorphonuclear Leukocyte ◽  
Polymorphonuclear Leukocytes ◽  
Intracellular Localization ◽  
The Other ◽  
Cytoplasmic Organelles

Rickettsia tsutsugamushi (Gilliam strain) was serially propagated in BHK-21 cell cultures and incubated with guinea pig peritoneal polymorphonuclear leukocytes to study the ultrastructural features of rickettsial uptake and entry into the leukocytes. Significant numbers of rickettsiae were phagocytized selectively by these leukocytes within 30 min. About one-half of these rickettsiae remained sequestered in phagosomes but the other one-half were free from the phagosome and localized directly in the polymorphonuclear leukocyte cytoplasm. Various stages of rickettsial release from the phagosomes were observed. Once free within the polymorphonuclear leukocyte cytoplasm, the rickettsiae were preferentially localized in the glycogen-packed areas which are devoid of lysosomes and other cytoplasmic organelles. This study indicates that rickettsiae phagocytized by polymorphonuclear leukocytes can escape from the phagosome into the cytoplasm.

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