Sister-chromatid exchanges induced by triethylenemelamine: in vivo and in vivo/in vitro studies in mouse and Chinese hamster bone marrow and spleen cells

1988 ◽  
Vol 206 (1) ◽  
pp. 73-82 ◽  
Author(s):  
J. Nath ◽  
G. Krishna ◽  
M. Petersen ◽  
T. Ong
1982 ◽  
Vol 1 (4) ◽  
pp. 387-392 ◽  
Author(s):  
G. Kirchner ◽  
U. Bayer

1 Most hair dyes contain the structural isomers ortho-, meta- and para-aminophenol which were investigated concerning their ability to induce sister chromatid exchanges (SCE) in cultured human lymphocytes in vitro and in Chinese hamster bone marrow cells in vivo. 2 In vitro only ortho-aminophenol significantly induced SCE in a dose-dependent manner. 3 In vivo none of the structural isomers increased significantly the SCE frequency. 4 It is concluded that ortho-aminophenol is a weak directly acting compound which is detoxified during its metabolism.


Hereditas ◽  
2009 ◽  
Vol 91 (1) ◽  
pp. 23-26 ◽  
Author(s):  
SAKARI KNUUTILA ◽  
ANU HARKKI ◽  
LEENA ROSSI ◽  
TUOMAS WESTERMARCK ◽  
LEO LAPPALAINEN ◽  
...  

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