Effects of amoxapine on serotonin uptake in human blood platelets of depressed patients and normal controls

1983 ◽  
Vol 9 (1) ◽  
pp. 29-35 ◽  
Author(s):  
Ramesh C. Arora ◽  
Herbert Y. Meltzer
Keyword(s):  
Human Blood ◽  
Blood Platelets ◽  
Serotonin Uptake ◽  
Depressed Patients ◽  
Normal Controls ◽  
Human Blood Platelets

Physostigmine effects on serotonin uptake in human blood platelets

1985 ◽  
Vol 109 (1) ◽  
pp. 91-96 ◽  
Author(s):  
Jeffrey L. Rausch ◽  
D.S. Janowsky ◽  
S.C. Risch ◽  
L.Y. Huey
Keyword(s):  
Human Blood ◽  
Blood Platelets ◽  
Serotonin Uptake ◽  
Human Blood Platelets

Effects of novel aggregation inhibitors on serotonin uptake by human blood platelets

1987 ◽  
Vol 923 (3) ◽  
pp. 443-450 ◽  
Author(s):  
Andrew Lasslo ◽  
Elwood O. Dillingham ◽  
Ramachander Gollamudi ◽  
Glarretter Carter-Burks
Keyword(s):  
Human Blood ◽  
Blood Platelets ◽  
Serotonin Uptake ◽  
Aggregation Inhibitors ◽  
Human Blood Platelets

The Active Serotonin Uptake and the Hypotonic Shock Response of Human Blood Platelets

1974 ◽  
Vol 32 (02/03) ◽  
pp. 391-404
Author(s):  
M. R Hardeman ◽  
Carina J. L. Heynens
Keyword(s):  
Human Blood ◽  
Blood Platelets ◽  
External Factors ◽  
Serotonin Uptake ◽  
Hypotonic Shock ◽  
Shock Response ◽  
Platelet Number ◽  
Ph Dependent ◽  
Human Blood Platelets

SummaryThe present paper is part of a study on the evaluation of the active serotonin uptake and the response to hypotonic shock as in vitro viability tests for human blood platelets.The extraction and fluorometric assay of serotonin in plasma and in platelets were further automated by the introduction of a dialyzer in the earlier described system. Furthermore, the influences of some external factors on both tests were investigated.The serotonin uptake as well as the hypotonic shock response were pH dependent and especially the latter was rather sensitive to small pH changes. Changes in the Na+ : K+ ratio were also found to influence both criteria significantly.The serotonin uptake appeared to be linearly dependent on the platelet number while, within a range of 200 X 103 - 450 X 103 platelets per fxl, the slope of the hypotonic shock response was the same.

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