Maximum variance of late component event related potentials (190–240 ms) in unmedicated schizophrenic patients

1995 ◽  
Vol 56 (3) ◽  
pp. 229-236 ◽  
Author(s):  
John Anderson ◽  
Evian Gordon ◽  
Robert J. Barry ◽  
Christopher Rennie ◽  
Pierre J.V. Beumont ◽  
...  
Keyword(s):  
Event Related Potentials ◽  
Late Component ◽  
Maximum Variance ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Component Event

The Modulation of Late Component Event Related Potentials by Pre-Stimulus EEG Theta Activity in ADHD

2001 ◽  
Vol 107 (3-4) ◽  
pp. 247-264 ◽  
Author(s):  
I. Lazzaro ◽  
E. Gordon ◽  
S. Whitmont ◽  
R. Meares ◽  
S. Clarke
Keyword(s):  
Event Related Potentials ◽  
Theta Activity ◽  
Late Component ◽  
Related Potentials ◽  
Component Event

An ERP Investigation of Semantic Priming, Repetition Priming, and Negative Priming in Schizophrenic Patients

2006 ◽  
Vol 20 (3) ◽  
pp. 195-211 ◽  
Author(s):  
Michael Wagner ◽  
Lioba Baving ◽  
Patrick Berg ◽  
Rudolf Cohen ◽  
Brigitte Rockstroh
Keyword(s):  
Negative Priming ◽  
Repetition Priming ◽  
Event Related Potentials ◽  
Decision Task ◽  
Positive Priming ◽  
Retrieval Processes ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Late Positive Complex ◽  
Automatic Memory

The processing of attended and nonattended stimuli in schizophrenic patients was examined with event-related potentials (ERPs) in a lexical decision task. In positive semantic and repetition priming the N400 amplitude did not differ between a group of 17 medicated schizophrenic patients and a group of 20 matched healthy controls. However, negative priming affected the N400 only in controls. Reaction time effects were dissociated from these ERP effects, with patients showing stronger positive priming than controls but identical negative priming. The semantic processes related to the N400 appear to be intact in schizophrenic patients, but patients seem to incorporate less context information (about the nonattended prime) in their episodic memory traces. A stronger increase of the posterior late positive complex in parallel to the stronger positive priming in schizophrenic patients may reflect relatively stronger automatic memory retrieval processes in patients.

Event-related potentials in drug-naive schizophrenic patients

1991 ◽  
Vol 29 (3) ◽  
pp. 265-272 ◽  
Author(s):  
Marguirite Radwan ◽  
Haggai Hermesh ◽  
Matti Mintz ◽  
Hanan Munitz
Keyword(s):  
Event Related Potentials ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Drug Naïve

Brain Indicators of Altered Attention and Information Processing in Schizophrenic Patients

1986 ◽  
Vol 148 (4) ◽  
pp. 414-420 ◽  
Author(s):  
K. Barrett ◽  
W. C. McCallum ◽  
P. V. Pocock
Keyword(s):  
Information Processing ◽  
Event Related Potentials ◽  
Normal Subjects ◽  
Detection Task ◽  
Auditory Target ◽  
Positive Potential ◽  
Stimulus Evaluation ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Target Detection Task

Late components of brain event-related potentials reflect aspects of selective attention, stimulus evaluation, and possibly memory update mechanisms. Several of these components were measured during an auditory target detection task, performed by 20 schizophrenic and 20 normal subjects. Both the amplitude of those components and a more general late amplitude measure were significantly reduced in schizophrenics, for both target and non-target stimuli. One general late amplitude measure, from the scalp vertex, could alone correctly classify 85% of patients and 95% of controls. The source of these differences may lie in a protracted positive potential shift.

scholarly journals Symmetrical electrophysiological brain responses to unilateral and bilateral auditory stimuli suggest disrupted spatial processing in schizophrenia

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Sara Sardari ◽  
Ali Mohammad Pourrahimi ◽  
Hossein Talebi ◽  
Shahrzad Mazhari
Keyword(s):  
Mismatch Negativity ◽  
Event Related Potentials ◽  
Frequency Discrimination ◽  
Stimulus Location ◽  
Spatial Processing ◽  
Healthy Individuals ◽  
Brain Responses ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Processing Deficits

Abstract Research has found auditory spatial processing deficits in patients with schizophrenia (SCZ), but no study has examined SCZ patients’ auditory spatial processing at both pre-attentional and attentional stages. To address this gap, we investigated schizophrenics’ brain responses to sounds originating from different locations (right, left, and bilateral sources). The event-related potentials (ERPs) of 25 chronic schizophrenic patients and 25 healthy subjects were compared. Mismatch negativity (MMN) in response to frequency and duration deviants was assessed. Two P3 components (P3a and P3b) were elicited via a frequency discrimination task, and MMN and P3 were recorded through separate monaural and dichotic stimulation paradigms. Our results corroborated the previously published finding that MMN, P3a, and P3b amplitudes are reduced in SCZ patients, but they showed no significant effect of stimulus location on either MMN or P3. These results indicated similarity between the SCZ patients and healthy individuals as regards patterns of ERP responses to stimuli that come from different directions. No evidence of auditory hemispatial bias in the SCZ patients was found, supporting the existence of non-lateralized spatial processing deficits in such patients and suggesting compensatory changes in the hemispheric laterality of patients’ brains.

Changes in Auditory P3 Event-related Potential in Schizophrenia and Depression

1987 ◽  
Vol 150 (2) ◽  
pp. 154-160 ◽  
Author(s):  
D. H. R. Blackwood ◽  
L. J. Whalley ◽  
J. E. Christie ◽  
I. M. Blackburn ◽  
D. M. St Clair ◽  
...  
Keyword(s):  
Event Related Potentials ◽  
Event Related Potential ◽  
Psychotic Symptoms ◽  
Auditory Information ◽  
Depressed Patients ◽  
Depressed Group ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Schizophrenic Group ◽  
P3 Amplitude

Event-related potentials during a two-tone discrimination task were recorded in 24 schizophrenic patients, 16 depressed patients and 59 control subjects. Recordings were made when patients were medication-free. Fourteen schizophrenic and 13 depressed patients were retested at 1 and 4 weeks after the start of treatment, and 13 schizophrenic patients were also tested between 6 and 24 months after the initial recordings. In the schizophrenic group, the P3 latency was significantly prolonged compared with that in the control and the depressed groups, and remained unchanged both after 4 weeks treatment with therapeutic doses of neuroleptic drugs and at long-term follow-up. In the depressed group, the P3 latency did not differ from that of controls. P3 amplitude by contrast was reduced in both the acutely depressed and schizophrenic groups and following treatment became normal in the depressed group but remained reduced in the schizophrenic group. It is suggested that a prolonged P3 latency and reduced P3 amplitude indicate an impairment of auditory information processing in some patients with schizophrenia which is independent of the presence of acute psychotic symptoms and is not influenced by neuroleptic medication.

Auditory event-related potentials and clinical scores in unmedicated schizophrenic patients

1999 ◽  
Vol 86 (3) ◽  
pp. 229-238 ◽  
Author(s):  
Annie Laurent ◽  
Luis Garcia-Larréa ◽  
Thierry d'Amato ◽  
Jean-Luc Bosson ◽  
Mohamed Saoud ◽  
...  
Keyword(s):  
Event Related Potentials ◽  
Auditory Event ◽  
Clinical Scores ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Auditory Event Related Potentials

scholarly journals Activity of BDNF and MMP-9 in Structural Synaptic Modulation in Patients with Schizophrenia Undergoing Rehabilitation

2020 ◽  
Author(s):  
Renata Markiewicz ◽  
Beata Dobrowolska ◽  
Tomasz Plech
Keyword(s):  
Event Related Potentials ◽  
Training Group ◽  
Quantitative Eeg ◽  
Rehabilitation Program ◽  
Biofeedback Training ◽  
Therapy Outcomes ◽  
Psychopathological Symptoms ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Group 2

Abstract The aim of the study was to evaluate the levels of brain derived neurotrophic factor (BDNF) and matrix metalloproteinase-9 (MMP-9) in two groups of schizophrenic patients receiving rehabilitation and to find out whether there existed relationships between the levels of these biomarkers and the severity of psychopathological symptoms, changes in event-related potentials (ERP), and quantitative EEG parameters. The study involved two groups of patients diagnosed with schizophrenia in remission who participated in a 12-week conventional rehabilitation program (Group 1) or Biofeedback training (Group 2). The following parameters were assessed: BDNF levels, MMP-9 levels, ERP, QEEG, and psychopathological symptoms (PANSS). (1) The magnitude of changes in the investigated parameters was similar in both groups. (2) Comparable therapy outcomes were obtained for all the dependent variables except for BDNF, whose levels were higher in the GSR-BF patients. GSR Biofeedback can be used as a new alternative to conventional rehabilitation. BDNF can be used as a target in the evaluation of the effectiveness of various rehabilitation modalities, in contrast to MMP-9, which, despite its role in neuromodulation, cannot be treated as a marker of treatment outcomes.

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