Phosphorus nuclear magnetic resonance studies on the calcium-dependent energy metabolism of rat cerebrum under conditions of increased potassium in vitro

1992 ◽  
Vol 12 (5) ◽  
pp. 596-605 ◽  
Author(s):  
Mitsuo Takei ◽  
Yoshihisa Kawano ◽  
Kazuhiro Yamada
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Energy Metabolism ◽  
Magnetic Resonance ◽  
Magnetic Resonance Studies ◽  
Calcium Dependent ◽  
Rat Cerebrum ◽  
Nuclear Magnetic

Nuclear magnetic resonance studies on calmodulin: calcium-dependent spectral change of proteolytic fragments

Biochemistry ◽  
1984 ◽  
Vol 23 (14) ◽  
pp. 3124-3128 ◽  
Author(s):  
Mitsuhiko Ikura ◽  
Toshifumi Hiraoki ◽  
Kunio Hikichi ◽  
Osamu Minowa ◽  
Haruhiko Yamaguchi ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Spectral Change ◽  
Magnetic Resonance Studies ◽  
Calcium Dependent ◽  
Nuclear Magnetic

scholarly journals N-[7-Chloro-4-[4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl] quinoline]-acetamide

Molbank ◽  
10.3390/m1213 ◽  
2021 ◽  
Vol 2021 (2) ◽  
pp. M1213
Author(s):  
Paolo Coghi ◽  
Jerome P. L. Ng ◽  
Ali Adnan Nasim ◽  
Vincent Kam Wai Wong
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Quantum Coherence ◽  
Biologically Active ◽  
Proton Nuclear Magnetic Resonance ◽  
Dipolar Cycloaddition ◽  
Heteronuclear Single Quantum Coherence ◽  
Pharmacokinetic Properties ◽  
Nuclear Magnetic

The 1,2,3-triazole is a well-known biologically active pharmacophore constructed by the copper-catalyzed azide–alkyne cycloaddition. We herein reported the synthesis of 4-amino-7-chloro-based [1,2,3]-triazole hybrids via Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition of 4-azido-7-chloroquinoline with an alkyne derivative of acetaminophen. The compound was fully characterized by Fourier-transform infrared (FTIR), proton nuclear magnetic resonance (1H-NMR), carbon-13 nuclear magnetic resonance (13C-NMR), heteronuclear single quantum coherence (HSQC), ultraviolet (UV) and high-resolution mass spectroscopies (HRMS). This compound was screened in vitro with different normal and cancer cell lines. The drug likeness of the compound was also investigated by predicting its pharmacokinetic properties.

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