Erythrocyte δ-aminolevulinic acid dehydratase in birds. II. The effects of lead exposure in vivo

Toxicology ◽  
1987 ◽  
Vol 45 (2) ◽  
pp. 165-175 ◽  
Author(s):  
A.M. Scheuhammer
2004 ◽  
Vol 150 (2) ◽  
pp. 171-178 ◽  
Author(s):  
Beata Dąbrowska-Bouta ◽  
Grzegorz Sulkowski ◽  
Lidia Strużyńska ◽  
Urszula Rafałowska

2005 ◽  
Vol 161 (Supplement_1) ◽  
pp. S46-S46
Author(s):  
J Weuve ◽  
K T Kelsey ◽  
J Schwartz ◽  
D Bellinger ◽  
P Rajan ◽  
...  

Author(s):  
Mona Sobhi Siha ◽  
Dalia Abdel-Hamid Shaker ◽  
Hebatalla Saad Teleb ◽  
Laila Ahmed Rashed

Lead exposure is associated with several health hazards among workers with different individual responses. We conducted this study to determine the possible effects of lead exposure on hematological parameters and kidney function of a group of Egyptian ammunition workers and the interaction of aminolevulinic acid dehydratase (ALAD) G177C gene polymorphisms as an effect modifier. Significant differences were observed between exposed workers with ALAD1-1 and ALAD1-2 genotypes in terms of blood lead level, hematological parameters and kidney function. It seems that δ-ALAD gene polymorphism may be an effect modifier and a marker of genetic susceptibility to lead toxicity.


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