Bolus injection of thrombolytic agents during cardio-pulmonary resuscitation for massive pulmonary embolism

This chapter recounts the history of thrombolytic agents, those agents currently available, and indications for use. Clinical agents have expanded over the 80 years since they were discovered, primarily in the pleural space. Thrombolytic agents can be administered systemically (i.e., intravenously) to treat ischemic stroke, massive pulmonary embolism (PE), and acute myocardial infarction. They also can be delivered directly to the site of a thrombus via catheter, also known as catheter-directed therapy (CDT). To perform CDT safely and effectively, an understanding of the pharmacology and technical aspects of delivering agents is critical. This chapter will review in detail the indications for use, contraindications to CDT, technical aspects, and specific recommendations for monitoring during use.

Download Full-text

Massive pulmonary embolism and cardio-pulmonary resuscitation leading to disseminated intravascular coagulation

Asian Journal of Transfusion Science ◽

10.4103/0973-6247.83266 ◽

2011 ◽

Vol 5 (2) ◽

pp. 188

Author(s):

Sachin Gupta ◽

Madiha Fyyaz ◽

Amitkumar Mehta

Keyword(s):

Pulmonary Embolism ◽

Disseminated Intravascular Coagulation ◽

Massive Pulmonary Embolism ◽

Intravascular Coagulation ◽

Cardio Pulmonary Resuscitation

Download Full-text

Abstract #860 Massive Pulmonary Embolism as the First Presentation of a Patient with Acromegaly

Endocrine Practice ◽

10.1016/s1530-891x(20)47346-x ◽

2018 ◽

Vol 24 ◽

pp. 204-205

Author(s):

Wajiha Gul ◽

Mehdi Errayes ◽

Buthaina Alowainati

Keyword(s):

Pulmonary Embolism ◽

Massive Pulmonary Embolism

Download Full-text

COVID-19 complicated by pulmonary embolism treated with catheter directed thrombectomy

VASA ◽

10.1024/0301-1526/a000880 ◽

2020 ◽

Vol 49 (4) ◽

pp. 333-337 ◽

Cited By ~ 3

Author(s):

Francisco Leonardo Galastri ◽

Leonardo Guedes Moreira Valle ◽

Breno Boueri Affonso ◽

Marcela Juliano Silva ◽

Rodrigo Gobbo Garcia ◽

...

Keyword(s):

Pulmonary Embolism ◽

High Risk ◽

Dynamic Process ◽

Therapeutic Option ◽

Massive Pulmonary Embolism ◽

Percutaneous Intervention ◽

Thromboembolic Events ◽

Emergency Center ◽

Catheter Directed Thrombolysis

Summary: COVID-19 is a recently identified illness that is associated with thromboembolic events. We report a case of pulmonary embolism in a patient with COVID-19, treated by catheter directed thrombectomy. A 57 year old patient presented to the emergency center with severe COVID-19 symptoms and developed massive pulmonary embolism. The patient was treated with catheter directed thrombolysis (CDT) and recovered completely. Coagulopathy associated with COVID-19 is present in all severe cases and is a dynamic process. We describe a case of massive/high risk pulmonary embolism, in a patient with COVID-19 receiving full anticoagulation, who was treated by percutaneous intervention. CDT can be an additional therapeutic option in patients with COVID-19 and pulmonary embolism that present with rapid clinical collapse.

Download Full-text

Endovascular repair of a spontaneous ilio-iliac fistula presenting as pulmonary embolism

VASA ◽

10.1024/0301-1526/a000100 ◽

2011 ◽

Vol 40 (3) ◽

pp. 246-250 ◽

Cited By ~ 4

Author(s):

Melas ◽

Saratzis ◽

Abbas ◽

Sarris ◽

Saratzis ◽

...

Keyword(s):

Pulmonary Embolism ◽

Endovascular Repair ◽

Therapeutic Option ◽

Artery Aneurysm ◽

Iliac Vein ◽

Massive Pulmonary Embolism ◽

Long Term Results ◽

Common Iliac Vein ◽

Iliac Artery Aneurysm ◽

Common Iliac Artery Aneurysm

Spontaneous rupture of a common iliac artery aneurysm into the common iliac vein is a rare phenomenon. We report the case of a 68 year old man admitted with acute cardiac failure and massive pulmonary embolism as a complication of a spontaneous ilio-iliac fistula, secondary to aneurysmal rupture. The aneurysm was successfully excluded using an aorto-uni-iliac stent graft. No complications were noted at 9 months follow-up. Arteriovenous fistulae should be considered in patients with aortic or iliac aneurysms who develop a pulmonary embolism or symptoms of venous congestion. Endovascular repair of these pathologies is a feasible therapeutic option; however long term results remain unknown.

Download Full-text