Induction of ornithine decarboxylase and histidine decarboxylase activities in rat colon mucosa after application of 12-o-tetradecanoylphorbol-13-acetate (TPA), sodium deoxycholate and indole

1988 ◽  
Vol 39 (1) ◽  
pp. 77-84 ◽  
Author(s):  
Yi Sun ◽  
Ying Li
Keyword(s):  
Ornithine Decarboxylase ◽  
Histidine Decarboxylase ◽  
Sodium Deoxycholate ◽  
Rat Colon ◽  
Colon Mucosa

Effects of phorbol ester and dexamethasone treatment on histidine decarboxylase and ornithine decarboxylase in basophilic cells

2001 ◽  
Vol 61 (9) ◽  
pp. 1101-1106 ◽  
Author(s):  
Ignacio Fajardo ◽  
Jose L Urdiales ◽  
Miguel A Medina ◽  
Francisca Sanchez-Jimenez
Keyword(s):  
Ornithine Decarboxylase ◽  
Phorbol Ester ◽  
Histidine Decarboxylase ◽  
Dexamethasone Treatment

Ornithine decarboxylase in rat small intestine: stimulation with food or insulin

1976 ◽  
Vol 231 (5) ◽  
pp. 1557-1561 ◽  
Author(s):  
DV Maudsley ◽  
J Leif ◽  
Y Kobayashi
Keyword(s):  
Enzyme Activity ◽  
Small Intestine ◽  
Ornithine Decarboxylase ◽  
Diamine Oxidase ◽  
Actinomycin D ◽  
Histidine Decarboxylase ◽  
Decarboxylase Activity ◽  
Adenosylmethionine Decarboxylase ◽  
Diamine Oxidase Activity ◽  
Similarities And Differences

Ornithine decarboxylase in the small intestine of starved rats was stimulated 3- to 10-fold by refeeding or administration of insulin. A peak is observed 3-5 h following treatment after which the enzyme activity rapidly declines. The rise in ornithine decarboxylase is reduced by actinomycin D or cycloheximide. The increase in enzyme activity occurs mainly in the duodenum and jejunum with less than a twofold change being observed in the ileum. A small (twofold) increase in S-adenosylmethionine decarboxylase activity in the small intestine was observed after food, but there was no change in diamine oxidase activity. Whereas pentagastrin and metiamide administration markedly stimulated histidine decarbosylase in the gastric mucosa, no consistent effect of these agents on ornithine decarboxylase in the small intestine was observed. The similarities and differences between histidine decarboxylase and ornithine decarboxylase are discussed.

The short-circuited everted sac of rat colon mucosa

1981 ◽  
Vol 178 (3) ◽  
pp. 247-256 ◽  
Author(s):  
K. J. Goerg ◽  
R. Wanitschke ◽  
K. H. Soergel ◽  
C. M. Wood ◽  
G. Nell
Keyword(s):  
Rat Colon ◽  
Colon Mucosa

Gastrin-mediated effects of omeprazole on rat colon mucosa

Surgery ◽  
1999 ◽  
Vol 126 (2) ◽  
pp. 272-278 ◽  
Author(s):  
Mary E. Klingensmith ◽  
Linda J. Neville ◽  
Eric Delpire ◽  
M.Michael Wolfe ◽  
David I. Soybel
Keyword(s):  
Rat Colon ◽  
Colon Mucosa ◽  
Mediated Effects

STUDIES ON THE MECHANISM OF ACTION OF ANGIOTENSIN ON FLUID TRANSPORT BY THE MUCOSA OF RAT DISTAL COLON

1972 ◽  
Vol 54 (3) ◽  
pp. 483-492 ◽  
Author(s):  
N. T. DAVIES ◽  
K. A. MUNDAY ◽  
B. J. PARSONS
Keyword(s):  
Protein Synthesis ◽  
Cyclic Amp ◽  
Rna Synthesis ◽  
Fluid Transport ◽  
Actinomycin D ◽  
Distal Colon ◽  
Rat Colon ◽  
Colon Mucosa ◽  
Rat Distal Colon ◽  
Stimulation Of

SUMMARY A study was made of the effects of cyclic AMP, theophylline, cycloheximide, puromycin and actinomycin D on the stimulation by angiotensin of fluid transport by sacs of rat colon mucosa. Cyclic AMP and theophylline, added together or separately, had no effect on fluid transport by colon sacs, suggesting that the stimulation of fluid transport after the application of angiotensin is not mediated through cyclic AMP. Cycloheximide and puromycin (used at concentrations which block colon protein synthesis by 50–90%) had no effect on fluid transport by control colon sacs, but completely blocked the stimulatory response of the colon to angiotensin. In contrast, actinomycin D (at a concentration which significantly inhibits RNA synthesis) did not affect fluid transport in control or angiotensin-stimulated colon sacs. The results are discussed in relation to the possibility that protein synthesis, at the stage of translation, is involved in the action of angiotensin on fluid transport by the colon.

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