This study takes a look at cultural practices around the world in terms of how they relate to being a contributing cause of malignant melanoma due to perceptions of skin colour and accepted tanning practices. This paper examines the effects of UV radiation in great detail and reviews skin cancer as a serious health risk due to overexposure and other factors. As part of the review of this global health threat, the demographic distribution of people who suffer from melanoma is also discussed. Currently, women between 31 and 50 years old are at the highest risk of developing skin cancer and, therefore, must be screened to reduce that risk, particularly given that malignant melanoma is better managed with earlier screening practices in middle-aged adults.