Pharmacologic characterization of fce 27262, a combined thromboxane synthase inhibitor (TXSI) and TXA2 receptor antagonist (TXRA)

Pharmacological Research ◽

10.1016/1043-6618(92)91185-j ◽

1992 ◽

Vol 26 ◽

pp. 238

Author(s):

P SALVATI

Keyword(s):

Receptor Antagonist ◽

Thromboxane Synthase ◽

Thromboxane Synthase Inhibitor ◽

Txa2 Receptor ◽

Txa2 Receptor Antagonist ◽

Synthase Inhibitor

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Additive antithrombotic effect of a thromboxane-synthase inhibitor (TXSI) associated to a fully effective dose of a TXA2-receptor antagonist (TXRA): Comparison with aspirin

Thrombosis Research ◽

10.1016/0049-3848(92)90398-t ◽

1992 ◽

Vol 65 ◽

pp. S42

Author(s):

P. Salvati ◽

L. Dho ◽

G. Ukmar ◽

L. Vaga ◽

O. Rimoldi ◽

...

Keyword(s):

Receptor Antagonist ◽

Effective Dose ◽

Antithrombotic Effect ◽

Thromboxane Synthase ◽

Thromboxane Synthase Inhibitor ◽

Txa2 Receptor ◽

Txa2 Receptor Antagonist ◽

Synthase Inhibitor

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Additive antithrombotic effect of a thromboxane-synthase inhibitor (TXSI) associated to a fully effective dose of a TXA2-receptor antagonist (TXRA): Comparison with aspirin

Thrombosis Research ◽

10.1016/0049-3848(92)90613-f ◽

1992 ◽

Vol 65 ◽

pp. S150

Keyword(s):

Receptor Antagonist ◽

Effective Dose ◽

Antithrombotic Effect ◽

Thromboxane Synthase ◽

Thromboxane Synthase Inhibitor ◽

Txa2 Receptor ◽

Txa2 Receptor Antagonist ◽

Synthase Inhibitor

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In Vitro and in Vivo Pharmacological Characterization of BM-613 [N-n-Pentyl-N′-[2-(4′-methylphenylamino)-5-nitrobenzenesulfonyl]urea], a Novel Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.104.079301 ◽

2004 ◽

Vol 313 (1) ◽

pp. 293-301 ◽

Author(s):

Julien Hanson ◽

Stephanie Rolin ◽

Denis Reynaud ◽

Na Qiao ◽

Leanne P. Kelley ◽

...

Keyword(s):

Receptor Antagonist ◽

Pharmacological Characterization ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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The dual thromboxane receptor antagonist and thromboxane synthase inhibitor EV-077 is a more potent inhibitor of platelet function than aspirin

Journal of Thrombosis and Haemostasis ◽

10.1111/j.1538-7836.2011.04446.x ◽

2011 ◽

Vol 9 (10) ◽

pp. 2109-2111 ◽

Author(s):

P. FONTANA ◽

P. ALBERTS ◽

K. S. SAKARIASSEN ◽

H. BOUNAMEAUX ◽

J.-P. MEYER ◽

...

Keyword(s):

Receptor Antagonist ◽

Platelet Function ◽

Potent Inhibitor ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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Basic pharmacophore of some antithrombotic agents with combined thromboxane receptor antagonist (TxRA)/thromboxane synthase inhibitor (TxSI) activity

Drug Development Research ◽

10.1002/(sici)1098-2299(199610)39:2<197::aid-ddr14>3.0.co;2-9 ◽

1996 ◽

Vol 39 (2) ◽

pp. 197-200 ◽

Author(s):

Yang Jie ◽

Hua Weiyi

Keyword(s):

Receptor Antagonist ◽

Antithrombotic Agents ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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Effects of a thromboxane receptor antagonist (NT-126) and a thromboxane synthase inhibitor (OKY-O46) on protamine-induced circulatory changes in dogs

Journal of Cardiothoracic and Vascular Anesthesia ◽

10.1053/jcan.2000.18449 ◽

2000 ◽

Vol 14 (6) ◽

pp. 687-692 ◽

Author(s):

Taro Mizutani ◽

Shinji Takahashi ◽

Shin-ichi Kihara ◽

Hidenori Toyooka

Keyword(s):

Receptor Antagonist ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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G 619, a Dual Thromboxane Synthase Inhibitor and Thromboxane A2 Receptor Antagonist, Reduces Myocardial Damage and Polymorpho-nuclear Leukocyte Accumulation following Coronary Artery Occlusion and Reperfusion in Rats

Pharmacology ◽

10.1159/000139094 ◽

1993 ◽

Vol 47 (3) ◽

pp. 167-175 ◽

Author(s):

Francesco Squadrito ◽

Mariapatrizia Ioculano ◽

Domenica Altavilla ◽

Basilia Zingarelli ◽

Patrizia Canale ◽

...

Keyword(s):

Coronary Artery ◽

Receptor Antagonist ◽

Myocardial Damage ◽

Coronary Artery Occlusion ◽

Artery Occlusion ◽

Thromboxane Synthase ◽

Leukocyte Accumulation ◽

Thromboxane Synthase Inhibitor ◽

Synthase Inhibitor

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Protective Effects of G 619, a Dual Thromboxane Synthase Inhibitor and Thromboxane A2 Receptor Antagonist, in Splanchnic Artery Occlusion Shock

Journal of Cardiovascular Pharmacology ◽

10.1097/00005344-199201000-00016 ◽

1992 ◽

Vol 19 (1) ◽

pp. 115-119 ◽

Author(s):

Francesco Squadrito ◽

Domenica Altavilla ◽

Basilia Zingarelli ◽

Maria P. Ioculano ◽

Giuseppe M. Campo ◽

...

Keyword(s):

Receptor Antagonist ◽

Thromboxane A2 ◽

Artery Occlusion ◽

Protective Effects ◽

Thromboxane Synthase ◽

Thromboxane A2 Receptor ◽

Thromboxane Synthase Inhibitor ◽

Splanchnic Artery ◽

Synthase Inhibitor

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Pharmacological Characterization of N-tert-Butyl-N′-[2-(4′-methylphenylamino)-5-nitrobenzenesulfonyl]urea (BM-573), a Novel Thromboxane A2 Receptor Antagonist and Thromboxane Synthase Inhibitor in a Rat Model of Arterial Thrombosis and Its Effects on Bleeding Time

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.103.063610 ◽

2004 ◽

Vol 309 (2) ◽

pp. 498-505 ◽

Author(s):

Jean-Michel Dogné ◽

Julien Hanson ◽

Xavier de Leval ◽

Philippe Kolh ◽

Vincent Tchana-Sato ◽

...

Keyword(s):

Receptor Antagonist ◽

Rat Model ◽

Arterial Thrombosis ◽

Bleeding Time ◽

Thromboxane A2 ◽

Pharmacological Characterization ◽

Thromboxane A2 Receptor ◽

Thromboxane Synthase Inhibitor ◽

Synthase Inhibitor

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Novel Agents Combining Platelet Activating Factor (PAF) Receptor Antagonist with Thromboxane Synthase Inhibitor (TxSI)

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(02)00005-7 ◽

2002 ◽

Vol 12 (5) ◽

pp. 771-774 ◽

Author(s):

Masakazu Fujita ◽

Taketsugu Seki ◽

Haruaki Inada ◽

Kazuhiro Shimizu ◽

Akane Takahama ◽

...

Keyword(s):

Receptor Antagonist ◽

Platelet Activating Factor ◽

Novel Agents ◽

Thromboxane Synthase ◽

Thromboxane Synthase Inhibitor ◽

Paf Receptor ◽

Synthase Inhibitor ◽

Paf Receptor Antagonist

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