DEPOSITION OF MONODISPERSE INSOLUBLE AEROSOL PARTICLES IN THE 0.005 TO 0.2 μm SIZE RANGE WITHIN THE HUMAN RESPIRATORY TRACT

1988 ◽  
pp. 41-49
Author(s):  
CH.F. SCHILLER ◽  
J. GEBHART ◽  
J. HEYDER ◽  
G. RUDOLF ◽  
W. STAHLHOFEN
Keyword(s):  
Respiratory Tract ◽  
Size Range ◽  
Aerosol Particles ◽  
Human Respiratory Tract

scholarly journals Prediction of Aerosol Deposition in the Human Respiratory Tract via Computational Models: A Review with Recent Updates

Atmosphere ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 137 ◽  
Author(s):  
Vu Khac Hoang Bui ◽  
Ju-Young Moon ◽  
Minhe Chae ◽  
Duckshin Park ◽  
Young-Chul Lee
Keyword(s):  
Respiratory Tract ◽  
Particle Deposition ◽  
Computational Models ◽  
Aerosol Particles ◽  
Three Dimensional ◽  
Aerosol Deposition ◽  
Research Area ◽  
Human Respiratory Tract

The measurement of deposited aerosol particles in the respiratory tract via in vivo and in vitro approaches is difficult due to those approaches’ many limitations. In order to overcome these obstacles, different computational models have been developed to predict the deposition of aerosol particles inside the lung. Recently, some remarkable models have been developed based on conventional semi-empirical models, one-dimensional whole-lung models, three-dimensional computational fluid dynamics models, and artificial neural networks for the prediction of aerosol-particle deposition with a high accuracy relative to experimental data. However, these models still have some disadvantages that should be overcome shortly. In this paper, we take a closer look at the current research trends as well as the future directions of this research area.

Measurement of the extrathoracic, tracheobronchial and alveolar deposition of aerosol particles in the human respiratory tract

1980 ◽  
Vol 11 (3) ◽  
pp. 234-235
Author(s):  
W. Stahlhofen ◽  
B. Eckhard ◽  
J. Gebhart ◽  
J. Heyder ◽  
B. Stuck
Keyword(s):  
Respiratory Tract ◽  
Aerosol Particles ◽  
Human Respiratory Tract

Deposition of Aerosol Particles in the Nasopharyngeal Region of the Human Respiratory Tract

Nature ◽  
1969 ◽  
Vol 221 (5187) ◽  
pp. 1254-1255 ◽  
Author(s):  
R. F. HOUNAM ◽  
A. BLACK ◽  
M. WALSH
Keyword(s):  
Respiratory Tract ◽  
Aerosol Particles ◽  
Human Respiratory Tract

Experimental studies of the total deposition of aerosol particles in the human respiratory tract

1973 ◽  
Vol 4 (3) ◽  
pp. 191-208 ◽  
Author(s):  
J. Heyder ◽  
J. Gebhart ◽  
G. Heigwer ◽  
C. Roth ◽  
W. Stahlhofen
Keyword(s):  
Respiratory Tract ◽  
Aerosol Particles ◽  
Experimental Studies ◽  
Human Respiratory Tract ◽  
Total Deposition

Effect of altered G levels on deposition of particulates in the human respiratory tract

1975 ◽  
Vol 38 (6) ◽  
pp. 955-960 ◽  
Author(s):  
R. A. Hoffman ◽  
J. Billingham
Keyword(s):  
Respiratory Tract ◽  
Size Range ◽  
Human Subjects ◽  
Linear Increase ◽  
Human Respiratory Tract ◽  
Primary Mode ◽  
Total Deposition ◽  
Unit Density ◽  
Rate Of Sedimentation

The primary mode of depositon of particles in the respiratory tract in the size range 0.5–10 mum diam (unit density) is sedimentation. The rate of sedimentation is directly proportional to the velocity of settling of the particle. Therefore, the total deposition of particles in the respiratory tract as well as the region of deposition is affected by changes in gravity. Human subjects were exposed to aerosols of 2.02-mum-diam polyvinyltoluene particles at 0, 0.5, 1.0, and 2.0 G. Total deposition was measured at each G level. Results indicate an almost linear increase in total deposition with increasing G levels over the range studied. The deposition measured at 1 G was less than reported in earlier experiments and the deposition at levels less than 1 G was less than had been calculated by Muir and Beeckmans. These data show that although sedimentation plays the major role in depostion of 2.02 mum particles, it is less than previously described.

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