Examples of physiologically based pharmacokinetic modeling applied to risk assessment

Physiologically Based Pharmacokinetic (PBPK) Modeling ◽

10.1016/b978-0-12-818596-4.00011-4 ◽

2020 ◽

pp. 281-299

Author(s):

Lisa M. Sweeney ◽

Jeffery M. Gearhart

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Risk Assessment of Predicted Serum Concentrations of Bisphenol A in Children and Adults Following Treatment with Dental Composite Restoratives, Dental Sealants, or Orthodontic Adhesives using Physiologically Based Pharmacokinetic Modeling

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2020.104839 ◽

2020 ◽

pp. 104839

Author(s):

Bradford D. Bagley ◽

Jordan N. Smith ◽

Justin G. Teeguarden

Keyword(s):

Risk Assessment ◽

Bisphenol A ◽

Pharmacokinetic Modeling ◽

Dental Composite ◽

Serum Concentrations ◽

Physiologically Based Pharmacokinetic Modeling ◽

Orthodontic Adhesives ◽

Physiologically Based Pharmacokinetic ◽

Dental Sealants ◽

Physiologically Based

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081030 (M10, B20) A tricholoethylene risk assessment using a Monte Carlo analysis of parameter uncertainty in conjunction with physiologically-based pharmacokinetic modeling

Insurance Mathematics and Economics ◽

10.1016/0167-6687(96)81409-0 ◽

1996 ◽

Vol 18 (2) ◽

pp. 140

Keyword(s):

Risk Assessment ◽

Monte Carlo ◽

Parameter Uncertainty ◽

Monte Carlo Analysis ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Tissue dosimetry, physiologically-based pharmacokinetic modeling, and cancer risk assessment

Cell Biology and Toxicology ◽

10.1007/bf00118411 ◽

1989 ◽

Vol 5 (4) ◽

pp. 405-415 ◽

Author(s):

Melvin E. Andersen

Keyword(s):

Risk Assessment ◽

Cancer Risk ◽

Pharmacokinetic Modeling ◽

Cancer Risk Assessment ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene

Inhalation Toxicology ◽

10.1080/08958378.2020.1715513 ◽

2019 ◽

Vol 31 (13-14) ◽

pp. 468-483 ◽

Author(s):

Harvey J. Clewell ◽

Jerry L. Campbell ◽

Cynthia Van Landingham ◽

Allison Franzen ◽

Miyoung Yoon ◽

...

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Modeling ◽

In Vitro Metabolism ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Response to “letter concerning: Clewell (2019) incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene.” (UIHT-2020-0053)

Inhalation Toxicology ◽

10.1080/08958378.2020.1817199 ◽

2020 ◽

Vol 32 (9-10) ◽

pp. 369-371

Author(s):

H. J. Clewell ◽

J. L. Campbell ◽

C. Van Landingham ◽

A. Franzen ◽

M. Yoon ◽

...

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Modeling ◽

In Vitro Metabolism ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Cancer risk assessment for the inhalation of 1,3-butadiene using physiologically based pharmacokinetic modeling

Bulletin of Environmental Contamination and Toxicology ◽

10.1007/bf00193342 ◽

1992 ◽

Vol 49 (1) ◽

Author(s):

WilliamH. Hallenbeck

Keyword(s):

Risk Assessment ◽

Cancer Risk ◽

Pharmacokinetic Modeling ◽

Cancer Risk Assessment ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Application of Physiologically Based Pharmacokinetic Modeling in Health Risk Assessment

Quantitative Modeling in Toxicology ◽

10.1002/9780470686263.ch19 ◽

2010 ◽

pp. 399-428

Author(s):

Harvey J. Clewell

Keyword(s):

Risk Assessment ◽

Health Risk ◽

Health Risk Assessment ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling in the Risk Assessment of Developmental Toxicants

Developmental Toxicology ◽

10.3109/9781420054385-13 ◽

2008 ◽

pp. 263-294

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling for Exposure and Risk Assessment

Encyclopedia of Environmental Health ◽

10.1016/b978-0-12-409548-9.10642-6 ◽

2019 ◽

pp. 233-238

Author(s):

Dingsheng Li

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Probabilistic risk assessment of gold nanoparticles after intravenous administration by integrating in vitro and in vivo toxicity with physiologically based pharmacokinetic modeling

Nanotoxicology ◽

10.1080/17435390.2018.1459922 ◽

2018 ◽

Vol 12 (5) ◽

pp. 453-469 ◽

Author(s):

Yi-Hsien Cheng ◽

Jim E. Riviere ◽

Nancy A. Monteiro-Riviere ◽

Zhoumeng Lin

Keyword(s):

Risk Assessment ◽

Gold Nanoparticles ◽

Intravenous Administration ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

In Vivo Toxicity ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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