Application of Physiologically Based Pharmacokinetic Modeling in Health Risk Assessment

Quantitative Modeling in Toxicology ◽

10.1002/9780470686263.ch19 ◽

2010 ◽

pp. 399-428

Author(s):

Harvey J. Clewell

Keyword(s):

Risk Assessment ◽

Health Risk ◽

Health Risk Assessment ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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The application of physiologically based pharmacokinetic modeling in human health risk assessment of hazardous substances

Toxicology Letters ◽

10.1016/0378-4274(95)03372-r ◽

1995 ◽

Vol 79 (1-3) ◽

pp. 207-217 ◽

Author(s):

H.J. Clewell

Keyword(s):

Risk Assessment ◽

Health Risk ◽

Human Health ◽

Health Risk Assessment ◽

Human Health Risk ◽

Pharmacokinetic Modeling ◽

Hazardous Substances ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Risk Assessment of Predicted Serum Concentrations of Bisphenol A in Children and Adults Following Treatment with Dental Composite Restoratives, Dental Sealants, or Orthodontic Adhesives using Physiologically Based Pharmacokinetic Modeling

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2020.104839 ◽

2020 ◽

pp. 104839

Author(s):

Bradford D. Bagley ◽

Jordan N. Smith ◽

Justin G. Teeguarden

Keyword(s):

Risk Assessment ◽

Bisphenol A ◽

Pharmacokinetic Modeling ◽

Dental Composite ◽

Serum Concentrations ◽

Physiologically Based Pharmacokinetic Modeling ◽

Orthodontic Adhesives ◽

Physiologically Based Pharmacokinetic ◽

Dental Sealants ◽

Physiologically Based

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081030 (M10, B20) A tricholoethylene risk assessment using a Monte Carlo analysis of parameter uncertainty in conjunction with physiologically-based pharmacokinetic modeling

Insurance Mathematics and Economics ◽

10.1016/0167-6687(96)81409-0 ◽

1996 ◽

Vol 18 (2) ◽

pp. 140

Keyword(s):

Risk Assessment ◽

Monte Carlo ◽

Parameter Uncertainty ◽

Monte Carlo Analysis ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Health Risk Assessment for Benzene Occupational Exposure Using Physiologically Based Pharmacokinetic Model and Dose-Response Model

2009 3rd International Conference on Bioinformatics and Biomedical Engineering ◽

10.1109/icbbe.2009.5162898 ◽

2009 ◽

Author(s):

Yang Wang ◽

Mao Liu ◽

Deyin Huang

Keyword(s):

Risk Assessment ◽

Occupational Exposure ◽

Health Risk ◽

Health Risk Assessment ◽

Dose Response ◽

Pharmacokinetic Model ◽

Response Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Examples of physiologically based pharmacokinetic modeling applied to risk assessment

Physiologically Based Pharmacokinetic (PBPK) Modeling ◽

10.1016/b978-0-12-818596-4.00011-4 ◽

2020 ◽

pp. 281-299

Author(s):

Lisa M. Sweeney ◽

Jeffery M. Gearhart

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling of the Glycol Ether, 2-butoxethanol, and Its Application in Human Health Risk Assessments and Exposure Guidelines

The Practical Applicability of Toxicokinetic Models in the Risk Assessment of Chemicals ◽

10.1007/978-94-017-3437-0_2 ◽

2002 ◽

pp. 7-39

Author(s):

Richard A. Corley

Keyword(s):

Health Risk ◽

Human Health ◽

Human Health Risk ◽

Pharmacokinetic Modeling ◽

Glycol Ether ◽

Risk Assessments ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Health Risk Assessments

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Physiologically based pharmacokinetic and pharmacodynamic modeling in health risk assessment and characterization of hazardous substances

Toxicology Letters ◽

10.1016/0378-4274(95)03357-q ◽

1995 ◽

Vol 79 (1-3) ◽

pp. 55-65 ◽

Author(s):

Hon-Wing Leung ◽

Dennis J. Paustenbach

Keyword(s):

Risk Assessment ◽

Health Risk ◽

Health Risk Assessment ◽

Hazardous Substances ◽

Pharmacodynamic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Tissue dosimetry, physiologically-based pharmacokinetic modeling, and cancer risk assessment

Cell Biology and Toxicology ◽

10.1007/bf00118411 ◽

1989 ◽

Vol 5 (4) ◽

pp. 405-415 ◽

Author(s):

Melvin E. Andersen

Keyword(s):

Risk Assessment ◽

Cancer Risk ◽

Pharmacokinetic Modeling ◽

Cancer Risk Assessment ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene

Inhalation Toxicology ◽

10.1080/08958378.2020.1715513 ◽

2019 ◽

Vol 31 (13-14) ◽

pp. 468-483 ◽

Author(s):

Harvey J. Clewell ◽

Jerry L. Campbell ◽

Cynthia Van Landingham ◽

Allison Franzen ◽

Miyoung Yoon ◽

...

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Modeling ◽

In Vitro Metabolism ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Response to “letter concerning: Clewell (2019) incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene.” (UIHT-2020-0053)

Inhalation Toxicology ◽

10.1080/08958378.2020.1817199 ◽

2020 ◽

Vol 32 (9-10) ◽

pp. 369-371

Author(s):

H. J. Clewell ◽

J. L. Campbell ◽

C. Van Landingham ◽

A. Franzen ◽

M. Yoon ◽

...

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Modeling ◽

In Vitro Metabolism ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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