Malignant bone tumors

2022 ◽  
pp. 563-582
Author(s):  
Katrina Winsnes ◽  
Noah Federman
Keyword(s):  
Bone Tumors ◽  
Malignant Bone Tumors

Scintigraphy with 99m Tc-Phosphonate and 67Gallium in Patients Suspected of Primary Bone Tumors

1982 ◽  
Vol 21 (04) ◽  
pp. 136-139 ◽  
Author(s):  
C.-J. Edeling
Keyword(s):  
Soft Tissue ◽  
Bone Scintigraphy ◽  
Primary Tumor ◽  
Bone Tumors ◽  
Whole Body ◽  
Skeletal Metastases ◽  
Malignant Bone Tumors ◽  
67Ga Scintigraphy ◽  
Primary Bone Tumors ◽  
Primary Bone

Whole-body scintigraphy with both 99mTc-phosphonate and 67Ga was performed on 92 patients suspected of primary bone tumors. In 46 patients with primary malignant bone tumors, scintigraphy with 99mTc-phosphonate disclosed the primary tumor in 44 cases and skeletal metastases in 11, and 67Ga scintigraphy detected the primary tumor in 43 cases, skeletal metastases in 6 cases and soft-tissue metastases in 8 cases. In 25 patients with secondary malignant bone tumors, bone scintigraphy visualized a single lesion in 10 cases and several lesions in 15 cases, and 67Ga scintigraphy detected the primary tumor in 17 cases, skeletal metastases in 17 cases and soft-tissue metastases in 9 cases. In 21 patients with benign bone disease positive uptake of 99mTc-phosphonate was recognized in 19 cases and uptake of 67Ga in 17 cases. It is concluded that bone scintigraphy should be used in patients suspected of primary bone tumors. If malignancy is suspected, 67Ga scintigraphy should be performed in addition.

MR-Derived CT-Like Images and Simulated Radiographs versus Conventional Radiography in Patients with Benign and Malignant Bone Tumors

2018 ◽  
Author(s):  
Alexandra Gersing ◽  
Daniela Muenzel ◽  
Felix Kopp ◽  
Benedikt Schwaiger ◽  
Carolin Knebel ◽  
...  
Keyword(s):  
Bone Tumors ◽  
Conventional Radiography ◽  
Malignant Bone Tumors

scholarly journals Malignant bone tumors in Kuwait

2005 ◽  
Vol 29 (6) ◽  
pp. 406-411 ◽  
Author(s):  
K. C. Katchy ◽  
F. Ziad ◽  
S. Alexander ◽  
H. Gad ◽  
M. Abdel Mota'al
Keyword(s):  
Bone Tumors ◽  
Malignant Bone Tumors

scholarly journals Experience with extendable prostheses for malignant bone tumors in children

2011 ◽  
Vol 110 (11) ◽  
pp. 711-715 ◽  
Author(s):  
Yukihiro Yoshida ◽  
Shunzo Osaka ◽  
Yasuaki Tokuhashi
Keyword(s):  
Bone Tumors ◽  
Malignant Bone Tumors

Diffusion kurtosis imaging assessment of the response to radiotherapy in a VX2 bone tumor model: an animal study

2021 ◽  
pp. 028418512198951
Author(s):  
Jia Guo ◽  
Cheng Dong ◽  
Zengjie Wu ◽  
Weikai Sun ◽  
Xiaoli Li ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Tumor Cell ◽  
Bone Tumors ◽  
Tumor Model ◽  
Poor Response ◽  
Early Response ◽  
Diffusion Kurtosis Imaging ◽  
Malignant Bone Tumors ◽  
Response Group ◽  
Diffusion Kurtosis

Background Neoadjuvant radiotherapy plays a vital role in the treatment of malignant bone tumors, and non-invasive imaging methods are needed to evaluate the response to treatment. Purpose To assess the value of diffusion kurtosis imaging (DKI) for monitoring early response to radiotherapy in malignant bone tumors. Material and Methods Treatment response was evaluated in a rabbit VX2 bone tumor model (n = 35) using magnetic resonance imaging (MRI), DKI, and histopathologic examinations. Subjects were divided into three groups: pre-treatment, post-treatment, and control groups. The post-treatment group was subclassified into good response and poor response groups according to the results of histopathologic examination. Apparent diffusion coefficient (ADC) and DKI parameters (mean diffusion coefficient [MD] and mean kurtosis [MK]) were recorded. The relationship between ADC, DKI parameters, and histopathologic changes after radiotherapy was determined using Pearson’s correlation coefficient. The diagnostic performance of these parameters was assessed using receiver operating characteristic analysis. Results MD in the good response group was higher after treatment than before treatment ( P < 0.001) and higher than that in the poor response group ( P = 0.009). MD was highly correlated with tumor cell density and apoptosis rate (r = −0.771, P < 0.001 and r = 0.625, P < 0.001, respectively). MD was superior to other parameters for determining the curative effect of radiotherapy, with a sensitivity of 75.0%, specificity of 100.0%, and area under the curve of 0.917 ( P < 0.001). Conclusion The correlations between MD, tumor cell density, and apoptosis suggest that MD could be useful for assessing the early response to radiotherapy in rabbit VX2 malignant bone tumors.

Use of Extendable Total Femoral Replacements in Children With Malignant Bone Tumors

1998 ◽  
Vol 357 ◽  
pp. 157-170 ◽  
Author(s):  
Oliver S. Schindler ◽  
Stephen R. Cannon ◽  
Timothy W.R. Briggs ◽  
Gordon W. Blunn ◽  
Robert J. Grimer ◽  
...  
Keyword(s):  
Bone Tumors ◽  
Malignant Bone Tumors

scholarly journals Primary Bone Tumors: Epidemiologic Comparison of 9200 Patients Treated at Beijing Ji Shui Tan Hospital, Beijing, China, With 10 165 Patients at Mayo Clinic, Rochester, Minnesota

2015 ◽  
Vol 139 (9) ◽  
pp. 1149-1155 ◽  
Author(s):  
Xiaohui Niu ◽  
Hairong Xu ◽  
Carrie Y. Inwards ◽  
Yuan Li ◽  
Yi Ding ◽  
...  
Keyword(s):  
Mayo Clinic ◽  
Bone Tumors ◽  
Age Distribution ◽  
Chinese Patients ◽  
Malignant Bone Tumors ◽  
Primary Bone Tumors ◽  
Male Predominance ◽  
Primary Bone ◽  
Different Populations ◽  
Epidemiologic Characteristics

Context Although primary bone tumors are extremely rare, the literature suggests that there are variations in the epidemiologic characteristics in different populations. The most frequently cited epidemiologic characteristics of primary bone tumors are derived from a large US series (Mayo Clinic), with no comparable study thus far performed in China. Objective To identify any potential epidemiologic differences between Chinese patients and a US series of patients. Design We performed a comparison study between 9200 patients treated at Beijing Ji Shui Tan Hospital (JST) and 10 165 patients treated at Mayo Clinic (MC), Rochester Minnesota. Detailed epidemiologic features were analyzed. Results We found that giant cell tumor and osteosarcoma have significantly higher incidences in the JST than the MC patients (P &lt; .001). However, JST patients had a significantly lower incidence of Ewing sarcoma, chordoma, fibrosarcoma, myeloma, and malignant lymphoma (P &lt; .001). For most benign and malignant bone tumors, the Chinese cohort had a more distinct male predominance than the US cohort. Malignant bone tumors had a monomodal age distribution in the JST patient group, with a bimodal age distribution in the MC cohort. Also, there were was a predilection for tumors of the femur and tibia among the JST patients (P &lt; .001). Conclusions Our data confirm that epidemiologic variations of primary bone tumors exist in different populations. Factors that may contribute to these observed differences are proposed and discussed.

Limb salvage surgery for malignant bone tumors of the extremities in children and adolescents

2009 ◽  
Vol 8 (11) ◽  
pp. 631-637 ◽  
Author(s):  
Zhen Wang ◽  
Zheng Guo ◽  
Xiangdong Li ◽  
Luyu Huang ◽  
Qiang Ji ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Limb Salvage ◽  
Bone Tumors ◽  
Salvage Surgery ◽  
Limb Salvage Surgery ◽  
Malignant Bone Tumors

A Carboxyl-Terminated Dendrimer Enables Osteolytic Lesion Targeting and Photothermal Ablation of Malignant Bone Tumors

2018 ◽  
Vol 11 (1) ◽  
pp. 160-168 ◽  
Author(s):  
Yang Yan ◽  
Xin Gao ◽  
Song Zhang ◽  
Yitong Wang ◽  
Zhengjie Zhou ◽  
...  
Keyword(s):  
Bone Tumors ◽  
Osteolytic Lesion ◽  
Malignant Bone Tumors ◽  
Photothermal Ablation

scholarly journals The Chemotherapy of Malignant Bone Tumors

1980 ◽  
Vol 3 (3) ◽  
pp. 101
Author(s):  
Ki Hong Choi ◽  
Chung Nam Kang ◽  
Jin Man Wang ◽  
Young Sung Park
Keyword(s):  
Bone Tumors ◽  
Malignant Bone Tumors
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