Precursor Lesions for Squamous Carcinoma in the Upper Aerodigestive Tract

2021 ◽  
pp. 1-62
Author(s):  
Edward Odell ◽  
Nina Gale ◽  
Selvam Thavaraj ◽  
Alfons Nadal ◽  
Nina Zidar ◽  
...  
Keyword(s):  
Squamous Carcinoma ◽  
Aerodigestive Tract ◽  
Precursor Lesions ◽  
Upper Aerodigestive Tract

Selective neck dissections for squamous carcinoma of the upper aerodigestive tract: Patterns of regional failure

Head & Neck ◽  
1999 ◽  
Vol 21 (6) ◽  
pp. 499-505 ◽  
Author(s):  
Robert M. Byers ◽  
Gary L. Clayman ◽  
Diane McGill ◽  
Todd Andrews ◽  
Ramon Paul Kare ◽  
...  
Keyword(s):  
Squamous Carcinoma ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract ◽  
Regional Failure

Prostaglandin E2 of the Upper Aerodigestive Tract

1987 ◽  
Vol 96 (2) ◽  
pp. 213-216 ◽  
Author(s):  
Jonas T. Johnson ◽  
Bruce S. Rabin ◽  
Robin L. Wagner
Keyword(s):  
Subsequent Development ◽  
Squamous Carcinoma ◽  
Normal Mucosa ◽  
Aerodigestive Tract ◽  
Second Primary ◽  
Prostaglandin E ◽  
Upper Aerodigestive Tract ◽  
Cell Infiltrate ◽  
Age Related ◽  
The Relationship

Mucosal specimens obtained from the upper aerodigestive tract of 101 patients were assayed for prostaglandin E2 (PGE2). Prostaglandin was detected in all specimens evaluated. Children and nonsmoking adults demonstrated lower concentrations of PGE2 than smoking adults. Tumor specimens from patients with squamous cell carcinoma of the upper aerodigestive tract demonstrated significantly increased levels of PGE2 (P<.05). Normal mucosa obtained from patients with squamous carcinoma elsewhere in their upper aerodigestive tract was found to contain significantly more PGE2 than that from adults without tumors (P<.05). The amount of PGE2 released from a tissue biopsy was not related to the amount of mononuclear cell infiltrate. No age-related trends in PGE2 levels were noted. Prostaglandin levels were higher in patients with advanced tumors in comparison to smaller tumors. The possible impact of elevated levels of PGE2 upon the immune system, the subsequent development of second primary carcinomas, and the relationship between PGE2 and the use of tobacco products is discussed.

Carcinogenesis in the Upper Aerodigestive Tract

1980 ◽  
Vol 13 (3) ◽  
pp. 403-412 ◽  
Author(s):  
Charles W. Vaughan ◽  
Freddy Homburger ◽  
Stanley M. Shapshay ◽  
Enrique Soto ◽  
Peter Bernfeld
Keyword(s):  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract
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