Herpetic Keratitis and Iritis

Author(s):  
Harpal S. Sandhu ◽  
Danielle Trief
Keyword(s):  
2018 ◽  
Vol 73 (2) ◽  
pp. 56-59
Author(s):  
E. Sereda ◽  
◽  
G. Drozhzhyna ◽  
T. Gaidamaka ◽  
◽  
...  

2009 ◽  
Vol 21 (5) ◽  
pp. 10-14
Author(s):  
P. Bezdetko ◽  
E. Iiyina ◽  
M. Lisenko ◽  
◽  
◽  
...  

1996 ◽  
Vol 40 (10) ◽  
pp. 2327-2331 ◽  
Author(s):  
W J O'Brien ◽  
J L Taylor ◽  
H Ankel ◽  
G Sitenga

Prostaglandin A2 (PGA2) inhibited the replication of herpes simplex virus type 1 in rabbit and human cornea stromal cells at concentrations of 1 to 5 microM while causing significant toxicity at 55 to 150 microM. Despite favorable therapeutic indices in cultured cells, PGA2 was not effective as a therapeutic agent in the treatment of herpetic keratitis in a rabbit model. The sequelae of disease appeared more severe in animals receiving PGA2 than in untreated or placebo-treated controls. The recovery of virus from tissues of latently infected rabbits was not affected by therapy. PGA2 therapy alone induced breakdown of the blood-aqueous barrier, indicating that pharmacologically active concentrations of drug were achieved in the eye. Thus, PGA2 had antiviral activity, but its proinflammatory effects appeared to be more detrimental than beneficial in the treatment of herpetic keratitis.


1980 ◽  
Vol 98 (10) ◽  
pp. 1755-1759 ◽  
Author(s):  
L. M. Cobo ◽  
D. J. Coster ◽  
N. S. C. Rice ◽  
B. R. Jones

2013 ◽  
Vol 208 (9) ◽  
pp. 1359-1365 ◽  
Author(s):  
Monique van Velzen ◽  
David A. M. C. van de Vijver ◽  
Freek B. van Loenen ◽  
Albert D. M. E. Osterhaus ◽  
Lies Remeijer ◽  
...  

1965 ◽  
Vol 59 (3) ◽  
pp. 473-476 ◽  
Author(s):  
Bernard B. Zucker ◽  
Andre J. Nahmias ◽  
Sidney Kibrick
Keyword(s):  

2003 ◽  
Vol 71 (1) ◽  
pp. 75-81 ◽  
Author(s):  
Kenichi Umene ◽  
Tomoyuki Inoue ◽  
Yoshitsugu Inoue ◽  
Yoshikazu Shimomura

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