Immobilization of bovine serum albumin as a sensitive biosensor for the detection of trace lead ion in solution by piezoelectric quartz crystal impedance

2007 ◽  
Vol 360 (1) ◽  
pp. 99-104 ◽  
Author(s):  
Jian Yin ◽  
Wanzhi Wei ◽  
Xiaoying Liu ◽  
Bo Kong ◽  
Ling Wu ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Quartz Crystal ◽  
Lead Ion ◽  
Piezoelectric Quartz ◽  
Piezoelectric Quartz Crystal

scholarly journals Improvement QCM Quality By Polystyrene Coating and Bovine Serum Albumin as Immobilization Agent

2019 ◽  
Vol 8 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Lalu A. Didik ◽  
Yahdi Yahdi ◽  
Masruroh Masruroh
Keyword(s):  
Thin Film ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Spin Coating ◽  
Bovine Serum ◽  
Quartz Crystal ◽  
Measuring System ◽  
Frequency Shifts ◽  
Impedance Analyzer ◽  
Coating Method

Polystyrene (PS) thin film with various concentration of mass (1%, 3%, and 5%) has been deposited onto Quartz Crystal Microbalance (QCM)  surface by a spin coating method. The purpose of this research is the improvement of Bovine Serum Albumin (BSA) immobilization into the QCM surface. The QCM resonance frequency has been investigated by means of Impedance Analyzer. The film thickness was calculated by the Sauerbrey equation. The surface roughness of the PS layer was observed by noncontact Topography Measuring System (TMS-1200). Calculation result using a Sauerbrey equation shows the thickness of the PS layer increases with the increasing PS concentration. The QCM/PS with 1% and 5% concentration of mass has rougher morphology and more frequency shifts caused by BSA injection compared to 3% concentration of PS

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