Effective Easing of the Side Effects of Copper Intrauterine Devices using Ultra-fine-grained Cu-0.4Mg Alloy

Author(s):  
Qianqian Fan ◽  
Guo Bao ◽  
Dongfeng Ge ◽  
Kun Wang ◽  
Mingming Sun ◽  
...  
2021 ◽  
Vol 5 (OOPSLA) ◽  
pp. 1-30
Author(s):  
Son Tuan Vu ◽  
Albert Cohen ◽  
Arnaud De Grandmaison ◽  
Christophe Guillon ◽  
Karine Heydemann

Software protections against side-channel and physical attacks are essential to the development of secure applications. Such protections are meaningful at machine code or micro-architectural level, but they typically do not carry observable semantics at source level. This renders them susceptible to miscompilation, and security engineers embed input/output side-effects to prevent optimizing compilers from altering them. Yet these side-effects are error-prone and compiler-dependent. The current practice involves analyzing the generated machine code to make sure security or privacy properties are still enforced. These side-effects may also be too expensive in fine-grained protections such as control-flow integrity. We introduce observations of the program state that are intrinsic to the correct execution of security protections, along with means to specify and preserve observations across the compilation flow. Such observations complement the input/output semantics-preservation contract of compilers. We introduce an opacification mechanism to preserve and enforce a partial ordering of observations. This approach is compatible with a production compiler and does not incur any modification to its optimization passes. We validate the effectiveness and performance of our approach on a range of benchmarks, expressing the secure compilation of these applications in terms of observations to be made at specific program points.


2005 ◽  
Vol 58 (5-6) ◽  
pp. 253-257
Author(s):  
Petar Draca ◽  
Branislava Jakovljevic

Introduction. The authors analyze contemporary methods of contraception. Regarding oral contraception, they point to agents which decrease the efficacy of oral contraception. They also deal with agents which increase the level of estrogen, thus increasing side effects (paracetamol, vitamin C). Oral contraceptives Oral contraceptives may also have an impact on the efficacy of some medications (anticonvulsants, antidepressants). Health risks of oral contraceptives are also mentioned, as well as WHO's, guidelines for women using contraceptives based on risks and benefits. Other methods of contraception The authors also offer criteria for use of bioactive intrauterine devices (IUD), with recommendations of WHO. Besides men's, there are women's condoms, which are very reliable protection against infections, but their negative side is that they are rather expensive. Bad sides of vaginal wash are also emphasized, although this method is rather widespread in the world. Conclusion. At the end, the authors quote the International Family Planning Fund (IFPF) which considers IUD to be the most reliable method of contraception nowadays. .


1967 ◽  
Vol 18 (3) ◽  
pp. 353-366 ◽  
Author(s):  
K. Mazher ◽  
I. Kamal ◽  
F. Hefnawi ◽  
M. Talaat ◽  
N. Younis ◽  
...  

1977 ◽  
Vol 9 (3) ◽  
pp. 317-323 ◽  
Author(s):  
A. E. Reading ◽  
J. R. Newton

SummaryThe high variability between centres in the incidence of side effects related to intrauterine devices (IUDs) is taken to indicate the need to direct research attention towards the context in which IUDs are inserted, as opposed to exclusive concern with the nature of the device. This paper considers the significance of psychological factors at the time of insertion in the light of recent studies indicating the benefits of adequate patient preparation.


1988 ◽  
pp. 295-311
Author(s):  
T. Rabe ◽  
B. Ellwanger ◽  
K. Grunwald ◽  
L. Kiesel ◽  
B. Runnebaum

2017 ◽  
Vol 11 (3) ◽  
pp. 742-747 ◽  
Author(s):  
Hira Imad Cheema ◽  
Ashutosh Gupta

Oral contraceptives have long been associated with liver injury. However, very little attention is paid to the metabolic side effects of hormone-releasing intrauterine devices (IUDs). These devices are generally considered safe and commonly used. We report for the first time acute liver injury associated with a levonorgestrel-releasing IUD. Our patient did not have any comorbidities that could have caused or exacerbated liver injury. A detailed workup and liver biopsy remained negative for any other potential cause of liver injury. The patient’s symptoms resolved with removal of the device. She remained symptom free on subsequent outpatient follow-ups.


2014 ◽  
Vol 48 (2) ◽  
Author(s):  
Muriel Norde ◽  
Karin Beijering

AbstractIt has long been recognized that many instances of change that have been discussed within the framework of grammaticalization studies notoriously defy categorization, for instance because they share properties of grammaticalization and lexicalization (Brinton & Traugott 2005), or because they share some properties of grammaticalization, but not all of them, as in the case of discourse markers (e.g. Ocampo 2006). In order to avoid these classification issues, we will argue that it is more useful to reduce grammaticalization and related changes to their “main mechanisms” (formal reanalysis and semantic reinterpretation), “primitive changes” (micro-changes on the levels of phonology, morphology, syntax, semantics and/or discourse), and “side effects” (e.g. obligatorification or layering). In grammaticalization and related changes, formal reanalysis and semantic reinterpretation tend to coincide with different sets of primitive changes. Primitive changes will be defined as ternary parameters with the values reduction, expansion, or zero, and it will be seen that they tend to cluster in different ways. Some of these clusters may coincide with changes traditionally labeled “grammaticalization”, “degrammaticalization”, or “lexicalization”, but changes may also cluster in alternative ways. This novel approach to composite changes we term the “clustering approach”, and we aim to show that this model of analysis allows for a more fine-grained account of composite changes than definition-based taxonomies.


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