scholarly journals Procedural sedation during transradial coronary angiography. Impact of opiod analgesia and inhalation sedation by 50% nitrous oxide/oxygen premix (Kalinox) on pain and radial artery spasm

2018 ◽  
Vol 10 (1) ◽  
pp. 26
Author(s):  
C. Birgy ◽  
N. Messas ◽  
J. Ristorto ◽  
S. Hess ◽  
A. Kayali ◽  
...  
2020 ◽  
Vol 9 (9) ◽  
pp. 2747
Author(s):  
Caroline Birgy ◽  
Antonin Trimaille ◽  
Nathan Messas ◽  
Jessica Ristorto ◽  
Anas Kayali ◽  
...  

With respect to the transfemoral approach, transradial procedures enable a drastic reduction of bleeding events and are associated with a reduction of mortality. Radial artery spasm (RAS) is one of the most common complications and may lead to patient discomfort and procedural failure. Currently, there is no consensus on the optimal sedation protocol to avoid RAS. The aim of this study was to investigate the respective impact of opioids analgesia and inhalation sedation with a 50% nitrous oxide/oxygen premix (Kalinox) on pain and occurrence of RAS during transradial coronary procedures. Consecutive patients undergoing transradial coronary angiography were prospectively enrolled in one, single center observational study (Nouvel Hôpital Civil, Strasbourg, France). Patients received opioids analgesia or inhalation sedation with Kalinox. The primary endpoints of the study were the incidence of a pain scale ≥5/10 and the occurrence of RAS. The secondary endpoints were the incidence of side effects. A total of 325 patients were enrolled (185 in the opioids analgesia group, 140 in the Kalinox group). RAS and pain scale ≥5 rates were not significantly different in the opioids analgesia and Kalinox groups (respectively 13.5% vs. 10.0% and 16.2% vs. 11.4%). Headache was more frequently observed in the Kalinox group (6.4% vs. 0.0%; p = 0.002). By multivariate analysis, female gender, BMI <25 kg/m2, puncture difficulty, the use of plastic needle and 6F sheath were identified as independent predictors of RAS. Procedural inhalation sedation by Kalinox is as safe as opioids analgesia during transradial coronary angiography.


2021 ◽  
Vol 31 (3) ◽  
pp. 433-435
Author(s):  
Kunal Gupta ◽  
Dimitrios Emmanouil ◽  
Amit Sethi

2011 ◽  
Vol 16 (2) ◽  
pp. 633-642 ◽  
Author(s):  
Martine Hennequin ◽  
Valérie Collado ◽  
Denise Faulks ◽  
Serge Koscielny ◽  
Peter Onody ◽  
...  

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