scholarly journals Total hemoglobin concentration in amniotic fluid is increased in intraamniotic infection/inflammation

2008 ◽  
Vol 199 (4) ◽  
pp. 426.e1-426.e7 ◽  
Author(s):  
Edi Vaisbuch ◽  
Roberto Romero ◽  
Offer Erez ◽  
Juan Pedro Kusanovic ◽  
Francesca Gotsch ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Hemoglobin Concentration ◽  
Intraamniotic Infection ◽  
Total Hemoglobin ◽  
Total Hemoglobin Concentration

scholarly journals Oxygen affinity of blood in altitude Sherpas

1979 ◽  
Vol 47 (2) ◽  
pp. 337-341 ◽  
Author(s):  
M. Samaja ◽  
A. Veicsteinas ◽  
P. Cerretelli
Keyword(s):  
Sea Level ◽  
Concentration Ratio ◽  
Oxygen Affinity ◽  
Hemoglobin Concentration ◽  
Cell Counts ◽  
Blood Cell Counts ◽  
Total Hemoglobin ◽  
The Mean ◽  
Total Hemoglobin Concentration ◽  
2,3 Dpg

Oxygen equilibrium curves on blood within 6 h from sampling have been estimated from polarographic measurements of oxyhemoglobin concentration, in 13 male 14- to 50-yr old Sherpas residing at 3,850 m above sea level (Kumjung, Nepal). In samples with red blood cell counts = 4.7 +/- 0.8 (SD) x 10(6)/mm3, total hemoglobin concentration [Hb] = 17.0 +/- 1.9 g/dl, and hematocrit = 53.3 +/- 5.0, the mean oxygen half-saturation of hemoglobin (P50) (pH = 7.4 and PCO2 = 40 Torr) was 27.3 +/- 1.8 Torr. The P50 of altitude Sherpas was not significantly different from that of acclimatized lowlanders (28.2 +/- 1.3; n = 7), sea-level Caucasian residents (26.5 +/- 1.0; n = 17), and Sherpas at sea level (27.1; n = 3). The 2,3-diphosphoglyceric acid-to-hemoglobin concentration ratio ([2,3-DPG]/[Hb]) in altitude Sherpas was 1.22 +/- 0.03, the same as that of acclimatized Caucasians (1.22 +/- 0.10). The Bohr effect measured for the blood of one altitude Sherpas by the ratio deltalog P50/deltapH was -0.32 and -0.45 at PCO2 levels of 40 and 20 Torr, respectively. These values are not significantly different from those found in Caucasians at sea level where deltalog P50/deltalpH was -0.35 and -0.42, respectively. It is concluded that the P50 in native highlanders is not significantly different from that observed in sea-level dwellers. [2,3-DPG]/[Hb] at altitude, both in natives and in newcomers, is 20% higher than in sea-level residents.

Optoacoustic monitoring of total hemoglobin concentration: In vitro and in vivo studies

2004 ◽  
Author(s):  
I. Y. Petrova ◽  
D. S. Prough ◽  
Y. Y. Petrov ◽  
H.- P. F. Brecht ◽  
C. Svensen ◽  
...  
Keyword(s):  
Hemoglobin Concentration ◽  
In Vivo Studies ◽  
Total Hemoglobin ◽  
Total Hemoglobin Concentration

Results of routine determination of clinically significant hemoglobin derivatives by multicomponent analysis.

1986 ◽  
Vol 32 (6) ◽  
pp. 972-978 ◽  
Author(s):  
A Zwart ◽  
E J van Kampen ◽  
W G Zijlstra
Keyword(s):  
Pulmonary Disease ◽  
Fetal Hemoglobin ◽  
Hemoglobin Concentration ◽  
Major Surgery ◽  
Chemical Laboratory ◽  
Total Hemoglobin ◽  
Clinically Significant ◽  
Blood Specimens ◽  
Total Hemoglobin Concentration

Abstract Our recently developed multiwavelength method for multi-component analysis of hemoglobin (Hb) derivatives (Clin Chem 1984;30:373-379) was adapted for routine use in the clinical chemical laboratory. The method was applied in 4066 determinations on blood specimens from patients awaiting major surgery (n = 3863) or visiting the outpatient department for pulmonary disease (n = 203). Mean total hemoglobin concentration was 141 (SD 14) g/L. The proportion of HbCO was slightly to moderately increased (1.5-10.0%) in 36.5% of all patients; in a few cases it was as high as 15%. Mean methemoglobin was 0.4% (SD 0.2%) in the surgical patients, but 1.5% (SD 0.8%) in the patients with pulmonary disease. In some patients of the latter group the proportion of methemoglobin amounted to 5%. Sulfhemoglobin was found less than 0.4% in all specimens. Interference by paraproteins and by increased concentrations of bilirubin and lipids in plasma was easily detected by means of the performance checks provided by the spectrophotometer (an HP 8451 UV/Vis). The method is equally suitable for measuring blood samples containing fetal hemoglobin.

scholarly journals CO-Oximetry interference by perflubron emulsion: comparison of hemolyzing and nonhemolyzing instruments

1998 ◽  
Vol 44 (10) ◽  
pp. 2183-2190 ◽  
Author(s):  
A P Shepherd ◽  
J M Steinke
Keyword(s):  
Preliminary Report ◽  
Effective Means ◽  
Hemoglobin Concentration ◽  
Blood Substitute ◽  
Surgical Patients ◽  
Clinical Use ◽  
Oxyhemoglobin Saturation ◽  
Blood Samples ◽  
Total Hemoglobin ◽  
Total Hemoglobin Concentration

Abstract Perflubron emulsion is expected to be in clinical use soon as a non-hemoglobin blood substitute. A preliminary report indicates that this new oxygen-carrying fluorocarbon interferes with the measurements of CO-oximeters. Therefore, we have quantified the interference that perflubron causes in the measurements of eight widely used oximeters and CO-oximeters. The AVL Omni 6, CC270, IL482, IL682, and OSM3 are conventional CO-oximeters that hemolyze blood samples before analyzing them. In contrast, the AVOXimeters 1000 and 4000 and the IL Synthesis 35 make their measurements without hemolyzing the samples. Because perflubron is expected to be used most frequently on surgical patients in a hemodiluted state, we conducted all tests on human erythrocytes suspended in plasma at a hemoglobin concentration standardized to 70 g/L (7 g/dL) and with oxyhemoglobin saturation set at 97%. When perflubron was added to the blood samples, the nonhemolyzing CO-oximeters were not seriously affected by perflubron concentrations in and above the therapeutic range. In contrast, some of the hemolyzing CO-oximeters experienced concentration-dependent interference in their measurements of all analytes except total hemoglobin concentration. Thus, we conclude that the nonhemolyzing CO-oximeters provide an effective means for determining whether a hemolyzing CO-oximeter is experiencing clinically important interference in blood from patients receiving perflubron.

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