12: Induction of labor versus expectant management in women with preterm prelabor rupture of membranes between 34 and 37 weeks–the PPROMEXIL-2 trial (ISRCTN05689407)

2012 ◽  
Vol 206 (1) ◽  
pp. S8-S9
Author(s):  
David van der Ham ◽  
Jantien van der Heijden ◽  
Brent Opmeer ◽  
Hans van Beek ◽  
Christine Willekes ◽  
...  
Keyword(s):  
Expectant Management ◽  
Induction Of Labor ◽  
Prelabor Rupture Of Membranes

Induction of Labor Versus Expectant Management for Prelabor Rupture of Membranes

2021 ◽  
pp. 74-80
Author(s):  
Adina Kern-Goldberger ◽  
Dena Goffman
Keyword(s):  
Cesarean Section ◽  
Lower Risk ◽  
Expectant Management ◽  
Neonatal Infection ◽  
Induction Of Labor ◽  
Prostaglandin E ◽  
Maternal Infection ◽  
Prelabor Rupture Of Membranes

The article highlights a landmark paper from 1992 addressing the management of women with prelabor rupture of membranes at term. The article reviews the paper in detail, highlights similar and relevant subsequent studies, and addresses up-to-date guidelines. The study compared the outcomes of 5041 with prelabor rupture of membranes at term. Women were either induced with oxytocin or vaginal prostaglandin or expectant management with subsequent induction as indicated. In women with prelabor rupture of the membranes at term, induction of labor with oxytocin or prostaglandin E2 and expectant management result in similar rates of neonatal infection and cesarean section. Induction of labor with intravenous oxytocin results in a lower risk of maternal infection than does expectant management. Women view induction of labor more positively than expectant management.

Economic analysis comparing induction of labor and expectant management in women with preterm prelabor rupture of membranes between 34 and 37 weeks (PPROMEXIL trial)

2014 ◽  
Vol 93 (4) ◽  
pp. 374-381 ◽  
Author(s):  
Sylvia M. C. Vijgen ◽  
David P. van der Ham ◽  
Denise Bijlenga ◽  
Johannes J. van Beek ◽  
Kitty W. M. Bloemenkamp ◽  
...  
Keyword(s):  
Economic Analysis ◽  
Expectant Management ◽  
Induction Of Labor ◽  
Prelabor Rupture Of Membranes

scholarly journals Induction of Labor versus Expectant Management in Women with Preterm Prelabor Rupture of Membranes between 34 and 37 Weeks: A Randomized Controlled Trial

PLoS Medicine ◽  
2012 ◽  
Vol 9 (4) ◽  
pp. e1001208 ◽  
Author(s):  
David P. van der Ham ◽  
Sylvia M. C. Vijgen ◽  
Jan G. Nijhuis ◽  
Johannes J. van Beek ◽  
Brent C. Opmeer ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Expectant Management ◽  
Induction Of Labor ◽  
Randomized Controlled ◽  
Prelabor Rupture Of Membranes

scholarly journals 757 Outcomes of elective induction of labor at 39 weeks compared to expectant management by age

2021 ◽  
Vol 224 (2) ◽  
pp. S474
Author(s):  
Alyssa R. Hersh ◽  
Eleanor M. Schmidt ◽  
Claire H. Packer ◽  
Bharti Garg ◽  
Aaron B. Caughey
Keyword(s):  
Expectant Management ◽  
Induction Of Labor ◽  
Elective Induction

scholarly journals Neonatal Survivability following Previable PPROM after Hospital Readmission for Intervention

2020 ◽  
Vol 10 (04) ◽  
pp. e395-e402
Author(s):  
Felicia LeMoine ◽  
Robert C. Moore ◽  
Andrew Chapple ◽  
Ferney A. Moore ◽  
Elizabeth Sutton
Keyword(s):  
Gestational Age ◽  
Neonatal Intensive Care ◽  
Intensive Care Unit Discharge ◽  
Expectant Management ◽  
Antibiotic Administration ◽  
Tertiary Referral Center ◽  
Membrane Rupture ◽  
South Central ◽  
Prelabor Rupture Of Membranes ◽  
Latency Duration

Abstract Objective To describe our hospital's experience following expectant management of previable preterm prelabor rupture of membranes (pPPROM). Study Design Retrospective review of neonatal survival and maternal and neonatal outcomes of pPPROM cases between 2012 and 2019 at a tertiary referral center in South Central Louisiana. Regression analyses were performed to identify predictors of neonatal survival. Results Of 81 cases of pPPROM prior to 23 weeks gestational age (WGA), 23 survived to neonatal intensive care unit discharge (28.3%) with gestational age at rupture ranging from 180/7 to 226/7 WGA. Increased latency (adjusted odds ratio [aOR] = 1.30, 95% confidence interval [CI] = 1.11, 1.52) and increased gestational age at rupture (aOR = 1.62, 95% CI = 1.19, 2.21) increased the probability of neonatal survival. Antibiotics prior to delivery were associated with increased latency duration (adjusted hazard ratio = 0.55, 95% CI = 0.42, 0.74). Conclusion Neonatal survival rate following pPPROM was 28.3%. Later gestational age at membrane rupture and increased latency periods are associated with increased neonatal survivability. Antibiotic administration following pPPROM increased latency duration.

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