Experience of 300 cases of prenatal fetoscopic open spina bifida repair: Report of the International Fetoscopic Neural Tube Defect Repair Consortium.

2021 ◽  
Author(s):  
Magdalena Sanz cortes ◽  
Ramen H. Chmait ◽  
Denise A. Lapa ◽  
Michael A. Belfort ◽  
Elena Carreras ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Neural Tube ◽  
Neural Tube Defect ◽  
Defect Repair ◽  
Open Spina Bifida

An economic analysis of prenatal fetoscopic versus open neural tube defect repair

2020 ◽  
Author(s):  
B. C. King ◽  
J. Hagan ◽  
R. Corroenne ◽  
A. A. Shamshirsaz ◽  
J. Espinoza ◽  
...  
Keyword(s):  
Economic Analysis ◽  
Neural Tube ◽  
Neural Tube Defect ◽  
Defect Repair

scholarly journals 1067: A cost analysis of prenatal fetoscopic versus open neural tube defect repair

2020 ◽  
Vol 222 (1) ◽  
pp. S658-S659
Author(s):  
Brian C. King ◽  
Magdalena Sanz Cortes ◽  
Romain Corroenne ◽  
Alireza A. Shamshirsaz ◽  
Jimmy Espinoza ◽  
...  
Keyword(s):  
Cost Analysis ◽  
Neural Tube ◽  
Neural Tube Defect ◽  
Defect Repair

scholarly journals 312: Initial results of a novel fetoscopic neural tube defect repair technique versus open fetal surgery

2016 ◽  
Vol 214 (1) ◽  
pp. S177-S178 ◽  
Author(s):  
Michael Belfort ◽  
William E. Whitehead ◽  
Alireza A. Shamshirsaz ◽  
Sundeep G. Keswani ◽  
Tim Lee ◽  
...  
Keyword(s):  
Neural Tube ◽  
Neural Tube Defect ◽  
Fetal Surgery ◽  
Repair Technique ◽  
Defect Repair ◽  
Initial Results

Myelomeningocele

2018 ◽  
Author(s):  
Joanne Spaliaras
Keyword(s):  
Spina Bifida ◽  
Neural Tube ◽  
Anesthetic Management ◽  
Spinal Column ◽  
Term Survival ◽  
Operative Repair ◽  
Associated Conditions ◽  
Vertebral Arch ◽  
Open Spina Bifida

Spina bifida is a defect in which the vertebral arch of the spinal column is either incompletely formed or absent. Failure of closure of the neural tube during the third week of gestation leads to the constellation of defects observed in patients with meningomyelocele or open spina bifida. Myelomeningocele is the most common neural tube defect and the most severe birth defect compatible with long-term survival. It is associated with several characteristic central nervous system anomalies. Leak of cerebrospinal fluid (CSF) is commonly observed. The major indication for early operative repair (within 48 hours of delivery) is prevention of infection. Protection of the exposed neural tissue from trauma and drying is essential. An understanding of the pathophysiology and associated conditions of myelomeningocele helps guide anesthetic management of these patients.

Concanavalin A binding of alpha-fetoprotein in amniotic fluid as an aid in the diagnosis of neural tube defects.

1981 ◽  
Vol 27 (10) ◽  
pp. 1658-1660 ◽  
Author(s):  
P K Buamah ◽  
P Taylor ◽  
A M Ward
Keyword(s):  
Spina Bifida ◽  
Amniotic Fluid ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
Concanavalin A ◽  
Gestational Age ◽  
Alpha Fetoprotein ◽  
Normal Outcome ◽  
Fetal Malformations ◽  
Open Spina Bifida

Abstract Concanavalin A nonreactive alpha-fetoprotein was determined in samples of amniotic fluid from 16 abnormal pregnancies complicated by anencephaly (7), open spina bifida (6), intra-uterine death (1), anencephaly with exomphalos (1), or open spina bifida with exomphalos (1), and in amniotic fluid from 50 normal pregnancies with gestational age between 13 and 24 weeks. In all 16 cases with fetal malformations, the proportion of nonreactive alpha-fetoprotein was significantly decreased (median 5.3%) as compared with amniotic fluid from pregnancies with a normal outcome (median 39.7%). The results confirm that this measurement is useful in the diagnosis of neural tube defects, especially when the concentration of alpha-fetoprotein in amniotic fluid is normal or only slightly above normal and gestational age is uncertain.

scholarly journals Craniorachischisis: first case reported in Madagascar

2018 ◽  
Vol 6 (4) ◽  
pp. 1454
Author(s):  
Hary F. Rabarikoto ◽  
Patrick S. Rakotozanany ◽  
Rosa L. Tsifiregna ◽  
Willy Ratovondrainy ◽  
Domoina M. A. Randriambololona
Keyword(s):  
Spinal Cord ◽  
Spina Bifida ◽  
Neural Tube Defect ◽  
Female Fetus ◽  
First Case ◽  
Medical Termination ◽  
Gestational Week ◽  
Brain And Spinal Cord ◽  
Severe Type ◽  
Open Spina Bifida

Craniorachischisis is the most severe type of neural tube defect in which almost the entire brain and spinal cord remain open. We report a case in a female fetus born at gestational week 38, with both anencephaly and open spina bifida. It was the second pregnancy of a 26-year-old woman. The first pregnancy had to be interrupted by a medical termination at 18th gestational week because of an anencephaly. We aim to report the first case documented in Madagascar.

Comparison of two fetoscopic open neural tube defect repair techniques: single‐ vs three‐layer closure

2020 ◽  
Vol 56 (4) ◽  
pp. 532-540 ◽  
Author(s):  
M. A. Belfort ◽  
W. E. Whitehead ◽  
A. A. Shamshirsaz ◽  
J. Espinoza ◽  
A. A. Nassr ◽  
...  
Keyword(s):  
Neural Tube ◽  
Neural Tube Defect ◽  
Defect Repair ◽  
Repair Techniques

scholarly journals Sirenomelia in Dicephalic parapagus twins discordant for anencephaly and spina bifida.

2020 ◽  
Vol 15 (1) ◽  
pp. 81-83
Author(s):  
Tripti Shrestha ◽  
Gehanath Baral ◽  
Nesuma Sedhain
Keyword(s):  
Spina Bifida ◽  
Key Words ◽  
Neural Tube ◽  
Neural Tube Defect ◽  
Congenital Anomalies ◽  
Rare Case ◽  
In Utero ◽  
Termination Of Pregnancy ◽  
High Incidence

An extremely rare case of sirenomelia in dicephalic parapagus twins discordant for anencephaly and spina bifida that was diagnosed after birth is presented. High incidence of congenital anomalies both with sirenomelia and parapagus twins independently make the prognosis much worse, with additional neural tube defect rendering it almost incompatible with life. Termination of pregnancy is advised when diagnosed in utero. Key words: anencephaly, dicephalic parapagus, spina bifida, sirenomelia

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