open spina bifida
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2021 ◽  
Vol 58 (S1) ◽  
pp. 51-51
Author(s):  
L. Trigo ◽  
M. Monson ◽  
A. Llanes ◽  
R. Chmait ◽  
D.A. Lapa

2021 ◽  
Vol 58 (S1) ◽  
pp. 67-68
Author(s):  
S. Agrawal ◽  
A. Al‐Refai ◽  
N. Abbasi ◽  
A. Kulkarni ◽  
J. Drake ◽  
...  

Author(s):  
M. Martínez-Rodríguez ◽  
J. Luna-García ◽  
H. López-Briones ◽  
R. Villalobos-Gómez ◽  
D. Saldívar-Rodríguez ◽  
...  

Author(s):  
L. Trigo ◽  
E. Eixarch ◽  
I. Bottura ◽  
M. Dalaqua ◽  
A. A. Barbosa ◽  
...  

2021 ◽  
Vol 2 (3) ◽  
pp. 118-123
Author(s):  
Olivier Leroij ◽  
Lennart Van der Veeken ◽  
Bettina Blaumeiser ◽  
Katrien Janssens

We present a case of a fetus with cranial abnormalities typical of open spina bifida but with an intact spine shown on both ultrasound and fetal MRI. Expert ultrasound examination revealed a very small tract between the spine and the skin, and a postmortem examination confirmed the diagnosis of a dorsal dermal sinus. Genetic analysis found a mosaic 3q23q27 duplication in the form of a marker chromosome. This case emphasizes that meticulous prenatal ultrasound examination has the potential to diagnose even closed subtypes of neural tube defects. Furthermore, with cerebral anomalies suggesting a spina bifida, other imaging techniques together with genetic tests and measurement of alpha-fetoprotein in the amniotic fluid should be performed.


2021 ◽  
Author(s):  
Romana Richterová ◽  
Branislav Kolarovszki ◽  
René Opšenák

Spina bifida is a neurodevelopmental disorder and belong to most common congenital malformations. It is a neural tube defect that originates within first 28 days after conception. Although survival rate of these patients had changed rapidly within last decades, neural tube defects are still cause of substantial part of children morbidity. Occult type of spina bifida is a simple nonunion of vertebral arch without causing any symptoms. Open defects according to degree of involvement of neural tissue cause symptoms such as paralysis of lower extremities, bladder and bowel morbidity, delay in development of cognitive functions of various severity and other possible complications affecting morbidity of these patients. Early diagnosis and treatment of open spina bifida and accompaying complications is crucial and largely affects the outome. Succesfull treatment requires lifelong cooperation of a whole range of specialists and guiding of treatment by primary care doctor. Survival and quality of life are associated with acces to proper medical and surgical treatment as well as community support systems. This chapter offers overview of this topic with emphasis on general management of patients suffering from this congenital malformation.


2021 ◽  
Author(s):  
René Opšenák ◽  
Romana Richterová ◽  
Branislav Kolarovszki

The spina bifida is a congenital anomaly that results in an abnormal formation of the spine and the spinal cord. The two dominant types of spinal dysraphism are based on appearance - open spina bifida if the lesion is visible and closed spina bifida if the lesion is not visible on the body surface. These conditions lead to a different spectrum of neurological effects according to the degree of neurulation disruption. The prevalence of neural tube defects has different rates among different ethnicity, geography, gender, and countries. Genetic, nutritional and environmental factors play a role in the etiology and pathogenesis of the spina bifida. Congenital anomalies in the vast majority concern children living in the early neonatal period who have important medical, social or educational needs. The lifetime cost of a child born with the spina bifida is estimated at over €500,000.


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