scholarly journals Preterm rupture of membranes following alternative hysterotomy for spina bifida open fetal surgery: systematic review

2022 ◽  
Vol 226 (1) ◽  
pp. S272
Author(s):  
Talita Micheletti ◽  
Karolyne Correa Lins ◽  
Mariana Ziliotto Sgnaolin ◽  
Marcelo Brandão da Silva
Keyword(s):  
Systematic Review ◽  
Spina Bifida ◽  
Fetal Surgery ◽  
Preterm Rupture Of Membranes

scholarly journals VP51.04: Options for intrauterine correction of spina bifida by open and fetoscopic fetal surgery: a systematic review

2021 ◽  
Vol 58 (S1) ◽  
pp. 306-306
Author(s):  
L. Lara‐Ávila ◽  
M. Martinez‐Rodriguez ◽  
R. Villalobos‐Gómez ◽  
H. López‐Briones ◽  
R. Cruz‐Martinez
Keyword(s):  
Systematic Review ◽  
Spina Bifida ◽  
Fetal Surgery

scholarly journals Safety and efficacy of fetal surgery techniques to close a spina bifida defect in the fetal lamb model: A systematic review

2018 ◽  
Vol 38 (4) ◽  
pp. 231-242 ◽  
Author(s):  
Luc Joyeux ◽  
Felix De Bie ◽  
Enrico Danzer ◽  
Tim Van Mieghem ◽  
Alan W. Flake ◽  
...  
Keyword(s):  
Systematic Review ◽  
Spina Bifida ◽  
Fetal Surgery ◽  
Safety And Efficacy ◽  
Fetal Lamb

scholarly journals ‘We did everything we could’– A qualitative study exploring the acceptability of maternal‐fetal surgery for spina bifida to parents

2021 ◽  
Author(s):  
Neeltje Crombag ◽  
Adalina Sacco ◽  
Bernadette Stocks ◽  
Philippe De Vloo ◽  
Johannes Van Der Merwe ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Qualitative Study ◽  
Fetal Surgery

scholarly journals Learning curves of open and endoscopic fetal spina bifida closure: systematic review and meta‐analysis

2020 ◽  
Vol 55 (6) ◽  
pp. 730-739 ◽  
Author(s):  
L. Joyeux ◽  
F. De Bie ◽  
E. Danzer ◽  
F. M. Russo ◽  
A. Javaux ◽  
...  
Keyword(s):  
Systematic Review ◽  
Spina Bifida ◽  
Meta Analysis ◽  
Learning Curves

scholarly journals Neurodevelopmental outcome of children with spina bifida aperta repaired prenatally vs postnatally: systematic review and meta-analysis

2019 ◽  
Vol 53 (3) ◽  
pp. 293-301 ◽  
Author(s):  
A. Inversetti ◽  
L. Van der Veeken ◽  
D. Thompson ◽  
K. Jansen ◽  
F. Van Calenbergh ◽  
...  
Keyword(s):  
Systematic Review ◽  
Spina Bifida ◽  
Meta Analysis ◽  
Neurodevelopmental Outcome ◽  
Spina Bifida Aperta

scholarly journals Open Spina Bifida: Why Not Fetal Surgery?

2018 ◽  
Vol 45 (6) ◽  
pp. 430-434 ◽  
Author(s):  
Luca Mazzone ◽  
Ueli Moehrlen ◽  
Barbara Casanova ◽  
Samira Ryf ◽  
Nicole Ochsenbein-Kölble ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Fetal Surgery ◽  
Open Spina Bifida

scholarly journals Fetal surgery for spina bifida aperta

2018 ◽  
Vol 103 (6) ◽  
pp. F589-F595 ◽  
Author(s):  
Luc Joyeux ◽  
Enrico Danzer ◽  
Alan W Flake ◽  
Jan Deprest
Keyword(s):  
Spina Bifida ◽  
Prolonged Exposure ◽  
Controlled Trial ◽  
Fetal Surgery ◽  
Neurological Deficits ◽  
Cerebrospinal Fluid Leakage ◽  
Essential Information ◽  
Ventriculoperitoneal Shunting ◽  
Spina Bifida Aperta ◽  
Randomised Controlled

Spina bifida aperta (SBA) is one of the most common congenital malformations. It can cause severe lifelong physical and neurodevelopmental disabilities. Experimental and clinical studies have shown that the neurological deficits associated with SBA are not simply caused by incomplete neurulation at the level of the lesion. Additional damage is caused by prolonged exposure of the spinal cord and nerves to the intrauterine environment and a suction gradient due to cerebrospinal fluid leakage, leading to progressive downward displacement of the hindbrain. This natural history can be reversed by prenatal repair. A randomised controlled trial demonstrated that mid-gestational maternal-fetal surgery for SBA decreases the need for ventriculoperitoneal shunting and hindbrain herniation at 12 months and improves neurological motor function at 30 months of age. This came at the price of maternal and fetal risks, the most relevant ones being increased prematurity and a persistent uterine corporeal scar. Recently minimally invasive fetal approaches have been introduced clinically yet they lack extensive experimental or clinical trials. We aim to provide clinicians with the essential information necessary to counsel SBA parents as the basis for considering referral of selected patients to expert fetal surgery centres. We review the reported clinical outcomes and discuss recent developments of potentially less invasive fetal SBA approaches.

Fetal surgery for spina bifida

The Lancet ◽  
1999 ◽  
Vol 353 (9150) ◽  
pp. 406 ◽  
Author(s):  
Gary Magram
Keyword(s):  
Spina Bifida ◽  
Fetal Surgery
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