scholarly journals Regular Sunscreen Use and Risk of Mortality: Long-Term Follow-up of a Skin Cancer Prevention Trial

2019 ◽  
Vol 56 (5) ◽  
pp. 742-746 ◽  
Author(s):  
Akiaja R. Lindstrom ◽  
Lena A. von Schuckmann ◽  
Maria Celia B. Hughes ◽  
Gail M. Williams ◽  
Adele C. Green ◽  
...  
2006 ◽  
Vol 42 (3) ◽  
pp. 171-176 ◽  
Author(s):  
Jolieke C. van der Pols ◽  
Gail M. Williams ◽  
Rachel E. Neale ◽  
Alexandra Clavarino ◽  
Adèle C. Green

BMJ Open ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. e018299 ◽  
Author(s):  
Titus Josef Brinker ◽  
Bianca Lisa Faria ◽  
Martina Gatzka ◽  
Olber Moreira de Faria ◽  
Markus V Heppt ◽  
...  

IntroductionThe incidence of melanoma is increasing faster than any other major cancer both in Brazil and worldwide. The Southeast of Brazil has especially high incidences of melanoma, and early detection is low. Exposure to UV radiation represents a primary risk factor for developing melanoma. Increasing attractiveness is a major motivation for adolescents for tanning. A medical student-delivered intervention that harnesses the broad availability of mobile phones as well as adolescents’ interest in their appearance may represent a novel method to improve skin cancer prevention.Methods and analysisWe developed a free mobile app (Sunface), which will be implemented in at least 30 secondary school classes, each with 21 students (at least 30 classes with 21 students for control) in February 2018 in Southeast Brazil via a novel method called mirroring. In a 45 min classroom seminar, the students’ altered three-dimensional selfies on tablets are ‘mirrored’ via a projector in front of their entire class, showing the effects of unprotected UV exposure on their future faces. External block randomisation via computer is performed on the class level with a 1:1 allocation. Sociodemographic data, as well as skin type, ancestry, UV protection behaviour and its predictors are measured via a paper–pencil questionnaire before as well as at 3 and 6 months postintervention. The primary end point is the group difference in the 30-day prevalence of daily sunscreen use at a 6-month follow-up. Secondary end points include (1) the difference in daily sunscreen use at a 3-month follow-up, (2) if a self-skin examination in accordance with the ABCDE rule was performed within the 6-month follow-up and (3) the number of tanning sessions.Ethics and disseminationEthical approval was obtained from the ethics committee of the University of Itauna. Results will be disseminated at conferences and in peer-reviewed journals.Trial registration numberNCT03178240; Pre-results.


2020 ◽  
pp. 96-108 ◽  
Author(s):  
Nawal Kassem ◽  
Leigh Anne Stout ◽  
Cynthia Hunter ◽  
Bryan Schneider ◽  
Milan Radovich

The identification of cancer-predisposing germline variants has potentially substantial clinical impact for patients and their families. Although management guidelines have been proposed for some genes, guidelines for other genes are lacking. This review focuses on the current surveillance and management guidelines for the most common hereditary cancer syndromes and discusses some of the most pivotal studies supporting the available guidelines. We also highlight the gaps in the identification of germline carriers, the cascade testing of at-risk relatives, and the challenges impeding the proper follow-up and optimal management of pathogenic germline carriers. The anticipated surge in the number of identified germline carriers, deficient management guidelines, poor cascade testing uptake, and long-term follow-up necessitate the development of multidisciplinary clinics as an obligatory step toward the improvement of cancer prevention.


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