Thoracoscopic Left Atrial Appendage Occlusion for Stroke Prevention Compared with Long-Term Warfarin Therapy in Patients With Nonvalvular Atrial Fibrillation

2019 ◽  
Vol 123 (1) ◽  
pp. 50-56 ◽  
Author(s):  
Mingjie Fu ◽  
Zheng Qin ◽  
Shuai Zheng ◽  
Yueping Li ◽  
Shiwei Yang ◽  
...  
2018 ◽  
Vol 11 (1) ◽  
pp. 75-82 ◽  
Author(s):  
Radoslaw Litwinowicz ◽  
Magdalena Bartus ◽  
Piotr Ceranowicz ◽  
Maciej Brzezinski ◽  
Bogusław Kapelak ◽  
...  

EP Europace ◽  
2017 ◽  
Vol 19 (suppl_1) ◽  
pp. i45-i45
Author(s):  
Anna Witkowska ◽  
Grzegorz Suwalski ◽  
Dominik Drobinski ◽  
Jakub Staromlynski ◽  
Radoslaw Smoczynski ◽  
...  

Author(s):  
Fareed Moses S. Collado ◽  
Claudia M. Lama von Buchwald ◽  
Christina K. Anderson ◽  
Nidhi Madan ◽  
Hussam S. Suradi ◽  
...  

Abstract The majority of embolic strokes in patients with nonvalvular atrial fibrillation are caused by thrombi in the left atrial appendage. It is projected that strokes related to atrial fibrillation will markedly increase in the future unless effective mitigation strategies are implemented. Systemic anticoagulation has been known to be highly effective in reducing stroke risk in patients with atrial fibrillation. However, bleeding complications and nonadherence are barriers to effective anticoagulation therapy. Surgical and percutaneous left atrial appendage occlusion devices are nonpharmacologic strategies to mitigate the challenges of drug therapy. We present a contemporary review of left atrial appendage occlusion for stroke prevention in nonvalvular atrial fibrillation. A thorough review of the history of surgical and percutaneous left atrial appendage occlusion devices, recent trials, and US Food and Drug Administration milestones of current left atrial appendage occlusion devices are discussed.


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