Left Atrial
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Anders Dahl Kramer ◽  
Kasper Korsholm ◽  
Andreas Kristensen ◽  
Lone Hvitfeldt Poulsen ◽  
Jens Erik Nielsen-Kudsk

Sjoerd Bouwmeester ◽  
Thomas P. Mast ◽  
Daniëlle C. J. Keulards ◽  
Anouk G. W. de Lepper ◽  
Ingeborg H. F. Herold ◽  

2021 ◽  
pp. 1-8
Filippo Angelini ◽  
Pier Paolo Bocchino ◽  
Mattia Peyracchia ◽  
Andrea Saglietto ◽  
Massimo Magnano ◽  

2021 ◽  
Issameddine Ajmi ◽  
Steffen Schnupp ◽  
Majdi Amami ◽  
Christian Mahnkopf

Aim: We aimed to study gender-specific differences in patients who underwent left atrial appendage closure (LAAC). Materials & methods: A total of 201 consecutive patients who underwent LAAC were enrolled. The EQ-5D-3L questionnaire was employed before and 3 months post-LAAC to study the quality of life. Results: Women had a higher score for Anxiety/Depression before implantation. Three months after LAAC, both groups showed a significant improvement in mobility, self-care and usual activities. The female gender had a significant improvement in health state 3 months after implantation than their male counterparts. Conclusion: Our data shows an improvement in mobility, self-care, usual activities and the overall health state in all patients after LAAC. This potential improvement, most likely caused by the discontinuation of oral anticoagulants, should be considered an indication for LAAC.

2021 ◽  
Ana Tanasa ◽  
Laura Tapoi ◽  
Carina Ureche ◽  
Radu Sascau ◽  
Cristian Statescu ◽  

T. Shchetynska-Marinova ◽  
M. Kranert ◽  
S. Baumann ◽  
V. Liebe ◽  
A. Grafen ◽  

Abstract Background Arterial stiffness (AS) has emerged as a strong predictor of cardiovascular (CV) diseases. Although increased AS has been described as a predictor of atrial fibrillation (AF), its role as a risk marker for AF recurrence has not yet been elucidated. Methods Patients with AF who underwent pulmonary vein isolation (PVI) were included in this study. Presence of AS was evaluated by measuring aortic distensibility (AD) of the descending aorta by transoesophageal echocardiography. Results In total, 151 patients (mean ± standard deviation (SD) age 71.9 ± 9.8 years) were enrolled and followed for a median duration of 21 months (interquartile range 15.0–31.0). During follow-up, AF recurred in 94 (62.3%) patients. AF recurrence was seen more frequently in patients with permanent AF (27% vs 46%, p = 0.03) and in those who had undergone prior PVI (9% vs 23%, p = 0.02). AD was significantly reduced in patients with AF recurrence (mean ± SD 2.6 ± 2.3 vs 1.5 ± 0.7 × 10−3 mm Hg−1, p < 0.0001), as well as left atrial volume index (LAVI) (mean ± SD 29 ± 12 vs 44 ± 15 ml/m2, p < 0.0001). Multivariable analysis revealed LAVI (odds ratio (OR) 2.9, 95% confidence interval (CI) 1.2–3.4) and AS (OR 3.6, 95% CI 2.8–4.1) as independent risk factors of AF recurrence. Conclusion Increased AS and left atrial size were independent predictors of AF recurrence after PVI. AD as surrogate marker of AS seemed to reflect the overall CV risk. In addition, AD was significantly correlated with left atrial size, which suggests that increased AS leads to atrial remodelling and thus to AF recurrence. Trial registration German registry for clinical studies (DRKS), DRKS00019007.

Fabrizio Rosati ◽  
Gijs E. Maat ◽  
Mattia A. E. Valente ◽  
Massimo A. Mariani ◽  
Stefano Benussi

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