Defining Ewing and Ewing-like small round cell tumors (SRCT): The need for molecular techniques in their categorization and differential diagnosis. A study of 200 cases

2016 ◽  
Vol 22 ◽  
pp. 25-32 ◽  
Author(s):  
Isidro Machado ◽  
Lara Navarro ◽  
Antonio Pellin ◽  
Samuel Navarro ◽  
Abbas Agaimy ◽  
...  
2006 ◽  
Vol 130 (5) ◽  
pp. 728-732 ◽  
Author(s):  
Fuju Chang

Abstract Desmoplastic small round cell tumor (DSRCT) is a recently recognized clinicopathologic entity that has a predilection for adolescent males and usually affects the abdominal cavity. Due to its uncommon nature, many pathologists lack experience with this tumor. The literature regarding DSRCT is reviewed with special attention to its histologic and cytologic diagnosis. Morphologic features of DSRCT and its immunohistochemical and cytogenetic profile are summarized and differential diagnosis with other small round cell tumors is discussed. As observed by both histologic and cytologic examinations, small round blue cells and fibrosclerotic stroma are the striking morphologic features of DSRCT. The typical immunohistochemical profile is characterized by coexpression of epithelial, mesenchymal, myogenic, and neural markers. Cytogenetically, this tumor harbors a specific karyotypic abnormality, namely t(11;22)(p13;q12). These features distinguish DSRCT from other members of the family of small round cell tumors.


1992 ◽  
Vol 20 (2) ◽  
pp. 130-135 ◽  
Author(s):  
Laura Sainati ◽  
Mario Stella ◽  
Anna Montaldi ◽  
Sonia Bolcato ◽  
Nicola Guercini ◽  
...  

2019 ◽  
Vol 85 ◽  
pp. S15
Author(s):  
Kıvılcım Eren Erdoğan

2015 ◽  
Vol 10 (5) ◽  
pp. 2991-2995 ◽  
Author(s):  
YUAN CAO ◽  
YING CHEN ◽  
LI YANG ◽  
ZI-HUA QIAN ◽  
SHU-GAO HAN ◽  
...  

2000 ◽  
Vol 13 (10) ◽  
pp. 1156-1160 ◽  
Author(s):  
Keisuke Kato ◽  
Kokoro Arai ◽  
Yukichi Tanaka ◽  
Rieko Ijiri ◽  
Yoshikazu Kato ◽  
...  

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