GS-8374, a Novel Phosphonate HIV Protease Inhibitor with Potent In Vitro Antiretroviral Activity, Low Metabolic Toxicity, and Favorable Resistance Profile

2007 ◽  
Vol 74 (3) ◽  
pp. A27-A27 ◽  
Author(s):  
C CALLEBAUT ◽  
K STRAY ◽  
L TSAI ◽  
L XU ◽  
G HE ◽  
...  
Keyword(s):  
Protease Inhibitor ◽  
Hiv Protease ◽  
Hiv Protease Inhibitor ◽  
Resistance Profile ◽  
Antiretroviral Activity

In vitro susceptibility of clinical isolates of HIV-1 to XM323, a non-peptidyl HIV protease inhibitor

AIDS ◽  
1994 ◽  
Vol 8 (6) ◽  
pp. 753-756 ◽  
Author(s):  
Dean L. Winslow ◽  
Douglas Mayers ◽  
Helen Scarnati ◽  
James Lane ◽  
Arlene Bincsik ◽  
...  
Keyword(s):  
Protease Inhibitor ◽  
Clinical Isolates ◽  
Hiv Protease ◽  
Hiv Protease Inhibitor ◽  
In Vitro Susceptibility ◽  
Hiv 1

A C2 Symmetry-Based HIV Protease Inhibitor, A77003, Irreversibly Inhibits Infectivity of HIV-1 In Vitro

1994 ◽  
Vol 10 (6) ◽  
pp. 735-743 ◽  
Author(s):  
SEIJI KAGEYAMA ◽  
DAVID T. HOEKZEMA ◽  
YOHKO MURAKAWA ◽  
EIJI KOJIMA ◽  
TAKUMA SHIRASAKA ◽  
...  
Keyword(s):  
Protease Inhibitor ◽  
Hiv Protease ◽  
Hiv Protease Inhibitor ◽  
Hiv 1

scholarly journals The HIV protease inhibitor, ritonavir, dysregulates human platelet function in vitro

2018 ◽  
Vol 169 ◽  
pp. 96-104 ◽  
Author(s):  
Shannon G. Loelius ◽  
Katie L. Lannan ◽  
Neil Blumberg ◽  
Richard P. Phipps ◽  
Sherry L. Spinelli
Keyword(s):  
Protease Inhibitor ◽  
Platelet Function ◽  
Human Platelet ◽  
Hiv Protease ◽  
Hiv Protease Inhibitor

scholarly journals Modeling Metabolic Effects of the HIV Protease Inhibitor Ritonavir In Vitro

2007 ◽  
Vol 171 (5) ◽  
pp. 1724-1725 ◽  
Author(s):  
Jeffrey Laurence ◽  
Rozbeh Modarresi ◽  
Xinwen Wang ◽  
Qizhi Yao ◽  
Changyi Chen
Keyword(s):  
Protease Inhibitor ◽  
Hiv Protease ◽  
Metabolic Effects ◽  
Hiv Protease Inhibitor

In Vitro Interaction of the HIV Protease Inhibitor Ritonavir with Herbal Constituents: Changes in P-gp and CYP3A4 Activity

2004 ◽  
Vol 11 (4) ◽  
pp. 262-277 ◽  
Author(s):  
Jignesh Patel ◽  
Balasubrahmanyam Buddha ◽  
Surajit Dey ◽  
Dhananjay Pal ◽  
Ashim K Mitra
Keyword(s):  
Protease Inhibitor ◽  
Hiv Protease ◽  
Cyp3a4 Activity ◽  
Hiv Protease Inhibitor ◽  
In Vitro Interaction

scholarly journals In vitro anti-human immunodeficiency virus (HIV) activity of XM323, a novel HIV protease inhibitor.

1993 ◽  
Vol 37 (12) ◽  
pp. 2606-2611 ◽  
Author(s):  
M J Otto ◽  
C D Reid ◽  
S Garber ◽  
P Y Lam ◽  
H Scarnati ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Protease Inhibitor ◽  
Hiv Protease ◽  
Hiv Protease Inhibitor ◽  
Immunodeficiency Virus

In vitro anti-HIV-1 activity of HIV protease inhibitor KNI-272 in resting and activated cells: implications for its combined use with AZT or ddI

1995 ◽  
Vol 28 (1) ◽  
pp. 25-38 ◽  
Author(s):  
Sudhichai Chokekijchai ◽  
Takuma Shirasaka ◽  
John N. Weinstein ◽  
Hiroaki Mitsuya
Keyword(s):  
Protease Inhibitor ◽  
Hiv Protease ◽  
Hiv Protease Inhibitor ◽  
Combined Use ◽  
Anti Hiv ◽  
Hiv 1
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