Sinotubular Junction Size Affects Aortic Root Geometry and Aortic Valve Function in the Aortic Valve Reimplantation Procedure: An In Vitro Study Using the Valsalva Graft

2007 ◽  
Vol 84 (4) ◽  
pp. 1214-1218 ◽  
Author(s):  
Daniele Maselli ◽  
Ruggero De Paulis ◽  
Raffaele Scaffa ◽  
Luca Weltert ◽  
Alessandro Bellisario ◽  
...  
Author(s):  
Neelakantan Saikrishnan ◽  
Nicole C. Milligan ◽  
Ajit P. Yoganathan

In about 1–2% of all live births, the human aortic valve only consists of two anomalous leaflets and is known as the bicuspid aortic valve (BAV). BAVs are the most common congenital cardiac anomaly, and are associated with significant valvular dysfunction, including calcific aortic stenosis (AS) and aortic regurgitation (AR), as well as aortic wall abnormalities including coarctation of the aorta, ascending aortic dilatation and aneurysms [1]. Many studies have proposed a common underlying genetic defect in progression of complications with BAVs [2]. However, other recent studies have also suggested that the altered hemodynamic environment associated with BAVs could also be responsible for accelerated disease progression in these patients [3, 4]. A recent in vitro study showed elevated levels of turbulence associated with BAVs, and indicated that fluid flow patterns in the aortic sinuses are also affected due to the altered valve morphology [5]. The present work seeks to compare the levels of turbulence in BAVs to pure trileaflet aortic stenosis models.


2017 ◽  
Vol 10 (3) ◽  
pp. S66
Author(s):  
Matheus Simonato ◽  
Ali Azadani ◽  
Michael Reardon ◽  
Gabriel Aldea ◽  
Georg Nickenig ◽  
...  

2004 ◽  
Vol 2004.5 (0) ◽  
pp. 185-186
Author(s):  
Shinnichi IIDA ◽  
Kenkichi OHBA ◽  
Tsutomu TAJIKAWA ◽  
Masataka YOSHIDA ◽  
Fuyo TSUKIYAMA

1998 ◽  
Vol 31 ◽  
pp. 323
Author(s):  
A.P. Yoganathan ◽  
R.S. Heinrich ◽  
R.A. Marcus ◽  
D.E. Gibson ◽  
A.E. Ensley ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document