Identification of urotensin II-related peptide as the urotensin II-immunoreactive molecule in the rat brain

2003 ◽  
Vol 310 (3) ◽  
pp. 860-868 ◽  
Author(s):  
Tsukasa Sugo ◽  
Yuko Murakami ◽  
Yukio Shimomura ◽  
Mioko Harada ◽  
Michiko Abe ◽  
...  
Keyword(s):  
Rat Brain ◽  
Urotensin Ii ◽  
Related Peptide

Concordant localization of functional urotensin II and urotensin II-related peptide binding sites in the rat brain: Atypical occurrence close to the fourth ventricle

2014 ◽  
Vol 522 (11) ◽  
pp. 2634-2649 ◽  
Author(s):  
Christine Bucharles ◽  
Patrice Bizet ◽  
Sébastien Arthaud ◽  
Arnaud Arabo ◽  
Jérôme Leprince ◽  
...  
Keyword(s):  
Rat Brain ◽  
Binding Sites ◽  
Fourth Ventricle ◽  
Peptide Binding ◽  
Urotensin Ii ◽  
Related Peptide

Characterization of the true ortholog of the urotensin II-related peptide (URP) gene in teleosts

2012 ◽  
Vol 177 (1) ◽  
pp. 205-212 ◽  
Author(s):  
Feng B. Quan ◽  
Marion Bougerol ◽  
Fanny Rigour ◽  
Natalia B. Kenigfest ◽  
Hervé Tostivint
Keyword(s):  
Urotensin Ii ◽  
Related Peptide

Urotensin core mimics that modulate the biological activity of urotensin-II related peptide but not urotensin-II

2017 ◽  
Vol 27 (15) ◽  
pp. 3412-3416 ◽  
Author(s):  
Martin Strack ◽  
Étienne Billard ◽  
David Chatenet ◽  
William D. Lubell
Keyword(s):  
Biological Activity ◽  
Urotensin Ii ◽  
Related Peptide

scholarly journals Urotensin receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

2019 ◽  
Vol 2019 (4) ◽  
Author(s):  
Anthony P. Davenport ◽  
Stephen A. Douglas ◽  
Alain Fournier ◽  
Adel Giaid ◽  
Henry Krum ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Neurosecretory System ◽  
Urotensin Ii ◽  
High Sequence Identity ◽  
Caudal Neurosecretory System ◽  
Amino Acid Peptide ◽  
Related Peptide ◽  
Human Sequence ◽  
Mature Mouse

The urotensin-II (U-II) receptor (UT, nomenclature as agreed by the NC-IUPHAR Subcommittee on the Urotensin receptor [26, 36, 89]) is activated by the endogenous dodecapeptide urotensin-II, originally isolated from the urophysis, the endocrine organ of the caudal neurosecretory system of teleost fish [7, 88]. Several structural forms of U-II exist in fish and amphibians. The goby orthologue was used to identify U-II as the cognate ligand for the predicted receptor encoded by the rat gene gpr14 [20, 62, 68, 70]. Human urotensin-II, an 11-amino-acid peptide [20], retains the cyclohexapeptide sequence of goby U-II that is thought to be important in ligand binding [53, 11]. This sequence is also conserved in the deduced amino-acid sequence of rat urotensin-II (14 amino-acids) and mouse urotensin-II (14 amino-acids), although the N-terminal is more divergent from the human sequence [19]. A second endogenous ligand for the UT has been discovered in rat [83]. This is the urotensin II-related peptide, an octapeptide that is derived from a different gene, but shares the C-terminal sequence (CFWKYCV) common to U-II from other species. Identical sequences to rat urotensin II-related peptide are predicted for the mature mouse and human peptides [32]. UT exhibits relatively high sequence identity with somatostatin, opioid and galanin receptors [89].

Effect of lithium on tachykinins, calcitonin gene-related peptide, and neuropeptide Y in rat brain

1990 ◽  
Vol 26 (2) ◽  
pp. 233-237 ◽  
Author(s):  
A. A. Mathé ◽  
J. Jousisto-Hanson ◽  
C. Stenfors ◽  
E. Theodorsson
Keyword(s):  
Neuropeptide Y ◽  
Rat Brain ◽  
Calcitonin Gene Related Peptide ◽  
Related Peptide ◽  
Calcitonin Gene

Urotensin II and urotensin II-related peptide (URP) in cardiac ischemia-reperfusion injury

Peptides ◽  
2008 ◽  
Vol 29 (5) ◽  
pp. 770-777 ◽  
Author(s):  
H.C.G. Prosser ◽  
M.E. Forster ◽  
A.M. Richards ◽  
C.J. Pemberton
Keyword(s):  
Reperfusion Injury ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Cardiac Ischemia ◽  
Urotensin Ii ◽  
Related Peptide

Development and Pharmacological Characterization of Conformationally Constrained Urotensin II-Related Peptide Agonists

2013 ◽  
Vol 56 (23) ◽  
pp. 9612-9622 ◽  
Author(s):  
David Chatenet ◽  
Benjamin Folch ◽  
Debby Feytens ◽  
Myriam Létourneau ◽  
Dirk Tourwé ◽  
...  
Keyword(s):  
Urotensin Ii ◽  
Pharmacological Characterization ◽  
Conformationally Constrained ◽  
Related Peptide
Sign in / Sign up

Export Citation Format

Share Document