Differential physiological, oxidative and antioxidative responses of cyanobacterium Anabaena sphaerica to attenuate malathion pesticide toxicity

2017 ◽  
Vol 11 ◽  
pp. 56-63 ◽  
Author(s):  
Sindhunath Chakraborty ◽  
Balkrishna Tiwari ◽  
Satya Shila Singh ◽  
Alok Kumar Srivastava ◽  
Arun Kumar Mishra
Author(s):  
Patrick Videau ◽  
Kaitlyn Wells ◽  
Arun Singh ◽  
Jessie Eiting ◽  
Philip Proteau ◽  
...  

Cyanobacteria are prolific producers of natural products and genome mining has shown that many orphan biosynthetic gene clusters can be found in sequenced cyanobacterial genomes. New tools and methodologies are required to investigate these biosynthetic gene clusters and here we present the use of <i>Anabaena </i>sp. strain PCC 7120 as a host for combinatorial biosynthesis of natural products using the indolactam natural products (lyngbyatoxin A, pendolmycin, and teleocidin B-4) as a test case. We were able to successfully produce all three compounds using codon optimized genes from Actinobacteria. We also introduce a new plasmid backbone based on the native <i>Anabaena</i>7120 plasmid pCC7120ζ and show that production of teleocidin B-4 can be accomplished using a two-plasmid system, which can be introduced by co-conjugation.


BIO-PROTOCOL ◽  
2016 ◽  
Vol 6 (15) ◽  
Author(s):  
Kangming Chen ◽  
Huilan Zhu ◽  
Liping Gu ◽  
Shengni Tian ◽  
Ruanbao Zhou

2015 ◽  
Vol 12 ◽  
pp. 463-469 ◽  
Author(s):  
J.I.S. Khattar ◽  
S. Kaur ◽  
S. Kaushal ◽  
Y. Singh ◽  
D.P. Singh ◽  
...  

1977 ◽  
Vol 252 (21) ◽  
pp. 7894-7900
Author(s):  
J.C. Meeks ◽  
C.P. Wolk ◽  
J. Thomas ◽  
W. Lockau ◽  
P.W. Shaffer ◽  
...  

Chemosphere ◽  
2021 ◽  
pp. 131456
Author(s):  
Lu Yang ◽  
Cuihong Sang ◽  
Yinghuan Wang ◽  
Wentao Liu ◽  
Weiyu Hao ◽  
...  

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