Advance chromatin extraction improves the performance of electropositive mixed-mode chromatography as a capture step and enables its integration with void-exclusion anion exchange chromatography as a two-column-step purification platform for monoclonal antibody production

Biochemical Engineering Journal ◽

10.1016/j.bej.2018.11.018 ◽

2019 ◽

Vol 142 ◽

pp. 145-152 ◽

Cited By ~ 2

Author(s):

Wenshuai Liu ◽

Yue Sun ◽

Jianli Yu ◽

Quan Chen ◽

Zixian Bao ◽

...

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Antibody Production ◽

Mixed Mode ◽

Anion Exchange Chromatography ◽

Exchange Chromatography ◽

Monoclonal Antibody Production

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A simple and efficient purification platform for monoclonal antibody production based on chromatin-directed cell culture clarification integrated with precipitation and void-exclusion anion exchange chromatography

Journal of Biotechnology ◽

10.1016/j.jbiotec.2016.08.014 ◽

2016 ◽

Vol 236 ◽

pp. 128-140 ◽

Cited By ~ 8

Author(s):

Quan Chen ◽

Sarah Maria Abdul Latiff ◽

Phyllicia Toh ◽

Xinying Peng ◽

Aina Hoi ◽

...

Keyword(s):

Cell Culture ◽

Monoclonal Antibody ◽

Anion Exchange ◽

Antibody Production ◽

Anion Exchange Chromatography ◽

Exchange Chromatography ◽

Monoclonal Antibody Production

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Strategies for developing design spaces for viral clearance by anion exchange chromatography during monoclonal antibody production

Biotechnology Progress ◽

10.1002/btpr.385 ◽

2010 ◽

Vol 26 (3) ◽

pp. 750-755 ◽

Cited By ~ 20

Author(s):

Daniel M. Strauss ◽

Tony Cano ◽

Nick Cai ◽

Heather Delucchi ◽

Magdalena Plancarte ◽

...

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Antibody Production ◽

Anion Exchange Chromatography ◽

Exchange Chromatography ◽

Viral Clearance ◽

Monoclonal Antibody Production

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Author response for "The prevention of an anomalous chromatographic behavior and the resulting successful removal of viruses from monoclonal antibody with an asymmetric charge distribution by using a membrane adsorber in highly efficient, anion‐exchange chromatography in flow‐through mode"

10.1002/btpr.2955/v2/response1 ◽

2019 ◽

Author(s):

Yumiko Masuda ◽

Yuka Ogino ◽

Kozo Yamaichi ◽

Yusuke Takahashi ◽

Koichi Nonaka ◽

...

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Charge Distribution ◽

Anion Exchange Chromatography ◽

Exchange Chromatography ◽

Author Response ◽

Chromatographic Behavior ◽

Successful Removal ◽

Flow Through ◽

Membrane Adsorber

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Decision letter for "The prevention of an anomalous chromatographic behavior and the resulting successful removal of viruses from monoclonal antibody with an asymmetric charge distribution by using a membrane adsorber in highly efficient, anion‐exchange chromatography in flow‐through mode"

10.1002/btpr.2955/v2/decision1 ◽

2019 ◽

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Charge Distribution ◽

Anion Exchange Chromatography ◽

Exchange Chromatography ◽

Chromatographic Behavior ◽

Highly Efficient ◽

Successful Removal ◽

Flow Through ◽

Membrane Adsorber

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Selectivity issues in targeted metabolomics: Separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography

Journal of Separation Science ◽

10.1002/jssc.201000412 ◽

2010 ◽

Vol 33 (21) ◽

pp. 3273-3282 ◽

Cited By ~ 62

Author(s):

Helmut Hinterwirth ◽

Michael Lämmerhofer ◽

Beatrix Preinerstorfer ◽

Andrea Gargano ◽

Roland Reischl ◽

...

Keyword(s):

Anion Exchange ◽

Mixed Mode ◽

Anion Exchange Chromatography ◽

Exchange Chromatography ◽

Targeted Metabolomics ◽

Hydrophilic Interaction ◽

Weak Anion Exchange Chromatography

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Preparation and evaluation of 2-methylimidazolium-functionalized silica as a mixed-mode stationary phase for hydrophilic interaction and anion-exchange chromatography

Journal of Chromatography A ◽

10.1016/j.chroma.2016.09.021 ◽

2016 ◽

Vol 1468 ◽

pp. 79-85 ◽

Cited By ~ 26

Author(s):

Beibei Yang ◽

Houmei Liu ◽

Jia Chen ◽

Ming Guan ◽

Hongdeng Qiu

Keyword(s):

Stationary Phase ◽

Anion Exchange ◽

Mixed Mode ◽

Anion Exchange Chromatography ◽

Exchange Chromatography ◽

Functionalized Silica ◽

Hydrophilic Interaction ◽

Preparation And Evaluation

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Characterization of Recombinant Monoclonal Antibody Charge Variants Using OFFGEL Fractionation, Weak Anion Exchange Chromatography, and Mass Spectrometry

Analytical Chemistry ◽

10.1021/acs.analchem.5b01452 ◽

2015 ◽

Vol 87 (12) ◽

pp. 6204-6211 ◽

Cited By ~ 28

Author(s):

Alyssa Neill ◽

Christine Nowak ◽

Rekha Patel ◽

Gomathinayagam Ponniah ◽

Nidia Gonzalez ◽

...

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibody ◽

Anion Exchange ◽

Anion Exchange Chromatography ◽

Exchange Chromatography ◽

Recombinant Monoclonal Antibody ◽

Charge Variants ◽

Weak Anion Exchange Chromatography

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Monoclonal antibody purification by medium-performance anion-exchange chromatography

Trends in Genetics ◽

10.1016/0168-9525(87)90189-2 ◽

1987 ◽

Vol 3 ◽

pp. 89

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Anion Exchange Chromatography ◽

Exchange Chromatography ◽

Antibody Purification

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Fouling of an anion exchange chromatography operation in a monoclonal antibody process: Visualization and kinetic studies

Biotechnology and Bioengineering ◽

10.1002/bit.24898 ◽

2013 ◽

Vol 110 (9) ◽

pp. 2425-2435 ◽

Cited By ~ 14

Author(s):

Edward J. Close ◽

Jeffrey R. Salm ◽

Timothy Iskra ◽

Eva Sørensen ◽

Daniel G. Bracewell

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Kinetic Studies ◽

Anion Exchange Chromatography ◽

Exchange Chromatography ◽

Process Visualization

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Decision letter for "The prevention of an anomalous chromatographic behavior and the resulting successful removal of viruses from monoclonal antibody with an asymmetric charge distribution by using a membrane adsorber in highly efficient, anion‐exchange chromatography in flow‐through mode"

10.1002/btpr.2955/v1/decision1 ◽

2019 ◽

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Charge Distribution ◽

Anion Exchange Chromatography ◽

Exchange Chromatography ◽

Chromatographic Behavior ◽

Highly Efficient ◽

Successful Removal ◽

Flow Through ◽

Membrane Adsorber

Download Full-text