A simple and efficient purification platform for monoclonal antibody production based on chromatin-directed cell culture clarification integrated with precipitation and void-exclusion anion exchange chromatography

Exchange Chromatography ◽

Advance chromatin extraction improves the performance of electropositive mixed-mode chromatography as a capture step and enables its integration with void-exclusion anion exchange chromatography as a two-column-step purification platform for monoclonal antibody production

Biochemical Engineering Journal ◽

10.1016/j.bej.2018.11.018 ◽

2019 ◽

Vol 142 ◽

pp. 145-152 ◽

Cited By ~ 2

Author(s):

Wenshuai Liu ◽

Yue Sun ◽

Jianli Yu ◽

Quan Chen ◽

Zixian Bao ◽

...

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Antibody Production ◽

Mixed Mode ◽

Exchange Chromatography ◽

Strategies for developing design spaces for viral clearance by anion exchange chromatography during monoclonal antibody production

Biotechnology Progress ◽

10.1002/btpr.385 ◽

2010 ◽

Vol 26 (3) ◽

pp. 750-755 ◽

Cited By ~ 20

Author(s):

Daniel M. Strauss ◽

Tony Cano ◽

Nick Cai ◽

Heather Delucchi ◽

Magdalena Plancarte ◽

...

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Antibody Production ◽

Exchange Chromatography ◽

Viral Clearance ◽

Author response for "The prevention of an anomalous chromatographic behavior and the resulting successful removal of viruses from monoclonal antibody with an asymmetric charge distribution by using a membrane adsorber in highly efficient, anion‐exchange chromatography in flow‐through mode"

10.1002/btpr.2955/v2/response1 ◽

2019 ◽

Author(s):

Yumiko Masuda ◽

Yuka Ogino ◽

Kozo Yamaichi ◽

Yusuke Takahashi ◽

Koichi Nonaka ◽

...

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Charge Distribution ◽

Exchange Chromatography ◽

Author Response ◽

Chromatographic Behavior ◽

Successful Removal ◽

Flow Through ◽

Membrane Adsorber

Decision letter for "The prevention of an anomalous chromatographic behavior and the resulting successful removal of viruses from monoclonal antibody with an asymmetric charge distribution by using a membrane adsorber in highly efficient, anion‐exchange chromatography in flow‐through mode"

10.1002/btpr.2955/v2/decision1 ◽

2019 ◽

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Charge Distribution ◽

Exchange Chromatography ◽

Chromatographic Behavior ◽

Highly Efficient ◽

Successful Removal ◽

Flow Through ◽

Membrane Adsorber

Stability of Monoclonal Antibody Production in Hybridoma Cell Culture

Flow Cytometry Applications in Cell Culture ◽

10.1201/9781003067467-5 ◽

2020 ◽

pp. 85-100

Author(s):

José M. Coco Martin ◽

E. Coen Beuvery

Keyword(s):

Cell Culture ◽

Monoclonal Antibody ◽

Antibody Production ◽

Monoclonal Antibody Production ◽

Hybridoma Cell Culture

Stability of Monoclonal Antibody Production in Hybridoma Cell Culture

Flow Cytometry Applications in Cell Culture ◽

10.4324/9781003067467-5 ◽

2020 ◽

pp. 85-100

Author(s):

José M. Coco Martin ◽

E. Coen Beuvery

Keyword(s):

Cell Culture ◽

Monoclonal Antibody ◽

Antibody Production ◽

Monoclonal Antibody Production ◽

Hybridoma Cell Culture

Cell culture processes for monoclonal antibody production

mAbs ◽

10.4161/mabs.2.5.12720 ◽

2010 ◽

Vol 2 (5) ◽

pp. 466-479 ◽

Cited By ~ 358

Author(s):

Feng Li ◽

Natarajan Vijayasankaran ◽

Amy (Yijuan) Shen ◽

Robert Kiss ◽

Ashraf Amanullah

Keyword(s):

Cell Culture ◽

Monoclonal Antibody ◽

Antibody Production ◽

Determination of cytidine 5′-monophospho-N-acetylneuraminic acid pool size in cell culture scale using high-performance anion-exchange chromatography with pulsed amperometric detection

Journal of Chromatography A ◽

10.1016/0021-9673(95)01157-9 ◽

1996 ◽

Vol 727 (2) ◽

pp. 223-230 ◽

Cited By ~ 14

Author(s):

Martin Fritsch ◽

Christoph C. Geilen ◽

Werner Reutter

Keyword(s):

Cell Culture ◽

Anion Exchange ◽

High Performance ◽

Amperometric Detection ◽

Exchange Chromatography ◽

Pulsed Amperometric Detection ◽

Acid Pool ◽

Acetylneuraminic Acid

Recombinant FIV virus gp160, 0.4, 0.6, 1.2 envelope protein from Escherichia coli; expression in eukaryote cell culture; monoclonal antibody production and recombinant vaccine production

Vaccine ◽

10.1016/0264-410x(93)90300-m ◽

1993 ◽

Vol 11 (4) ◽

pp. 488

Keyword(s):

Escherichia Coli ◽

Cell Culture ◽

Monoclonal Antibody ◽

Antibody Production ◽

Envelope Protein ◽

Recombinant Vaccine ◽

Vaccine Production ◽

Monoclonal Antibody Production ◽

Escherichia Coli Expression

Evaluation of cell culture in microfluidic chips for application in monoclonal antibody production

Microelectronic Engineering ◽

10.1016/j.mee.2016.03.059 ◽

2016 ◽

Vol 158 ◽

pp. 126-129 ◽

Cited By ~ 9

Author(s):

A. Peñaherrera ◽

C. Payés ◽

M. Sierra-Rodero ◽

M. Vega ◽

G. Rosero ◽

...

Keyword(s):

Cell Culture ◽

Monoclonal Antibody ◽

Antibody Production ◽

Microfluidic Chips ◽