The in-vitro bioactivity of mesoporous bioactive glasses

Biomaterials ◽  
2006 ◽  
Vol 27 (18) ◽  
pp. 3396-3403 ◽  
Author(s):  
Xiaoxia Yan ◽  
Xiaohui Huang ◽  
Chengzhong Yu ◽  
Hexiang Deng ◽  
Yi Wang ◽  
...  
Keyword(s):  
In Vitro Bioactivity ◽  
Bioactive Glasses

scholarly journals Bone Regeneration by Novel Bioactive Glasses Containing Strontium and/or Magnesium: A Preliminary In-Vivo Study

Materials ◽  
2018 ◽  
Vol 11 (11) ◽  
pp. 2223 ◽  
Author(s):  
Devis Bellucci ◽  
Valeria Cannillo ◽  
Alexandre Anesi ◽  
Roberta Salvatori ◽  
Luigi Chiarini ◽  
...  
Keyword(s):  
Statistical Significance ◽  
Formation Processes ◽  
Complete Dissolution ◽  
In Vitro Bioactivity ◽  
Bioactive Glasses ◽  
Beneficial Effects ◽  
Glass Dissolution

In this work, a set of novel bioactive glasses have been tested in vivo in an animal model. The new compositions, characterized by an exceptional thermal stability and high in vitro bioactivity, contain strontium and/or magnesium, whose biological benefits are well documented in the literature. To simulate a long-term implant and to study the effect of the complete dissolution of glasses, samples were implanted in the mid-shaft of rabbits’ femur and analyzed 60 days after the surgery; such samples were in undersized powder form. The statistical significance with respect to the type of bioactive glass was analyzed by Kruskal–Wallis test. The results show high levels of bone remodeling, several new bone formations containing granules of calcium phosphate (sometimes with amounts of strontium and/or magnesium), and the absence of adverse effects on bone processes due to the almost complete glass dissolution. In vivo results confirming the cell culture outcomes of a previous study highlighted that these novel bioglasses had osteostimulative effect without adverse skeletal reaction, thus indicating possible beneficial effects on bone formation processes. The presence of strontium in the glasses seems to be particularly interesting.

Acetic acid derived mesoporous bioactive glasses with an enhanced in vitro bioactivity

2009 ◽  
Vol 355 (52-54) ◽  
pp. 2583-2587 ◽  
Author(s):  
Bo Lei ◽  
Xiaofeng Chen ◽  
Yingjun Wang ◽  
Naru Zhao ◽  
Chang Du ◽  
...  
Keyword(s):  
Acetic Acid ◽  
In Vitro Bioactivity ◽  
Bioactive Glasses

Synthesis, characterization and in vitro bioactivity of mesoporous copper silicate bioactive glasses

2018 ◽  
Vol 44 (2) ◽  
pp. 2390-2399 ◽  
Author(s):  
Razieh Koohkan ◽  
Tabassom Hooshmand ◽  
Mohammadreza Tahriri ◽  
Davod Mohebbi-Kalhori
Keyword(s):  
In Vitro Bioactivity ◽  
Bioactive Glasses ◽  
Copper Silicate
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