Design, synthesis and biological evaluation of resveratrol-cinnamoyl derivates as tubulin polymerization inhibitors targeting the colchicine binding site

Synthesis and biological evaluation of novel shikonin-benzo[b]furan derivatives as tubulin polymerization inhibitors targeting the colchicine binding site

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112105 ◽

2020 ◽

Vol 190 ◽

pp. 112105 ◽

Cited By ~ 2

Author(s):

Yu-Ying Shao ◽

Yong Yin ◽

Bao-Ping Lian ◽

Jia-Fu Leng ◽

Yuan-Zheng Xia ◽

...

Keyword(s):

Binding Site ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Furan Derivatives ◽

Colchicine Binding Site ◽

Design, Synthesis and Biological Evaluation of 1,4-Disubstituted-3,4-dihydroisoquinoline Compounds as New Tubulin Polymerization Inhibitors

International Journal of Molecular Sciences ◽

10.3390/ijms160510173 ◽

2015 ◽

Vol 16 (12) ◽

pp. 10173-10184 ◽

Cited By ~ 1

Author(s):

Ling Zhang ◽

Yunlong Song ◽

Jingjing Huang ◽

Jia Liu ◽

Wenwen Zhu ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Design, Synthesis and Biological Evaluation of Novel Acridine and Quinoline Derivatives as Tubulin Polymerization Inhibitors with Anticancer Activities

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2021.116376 ◽

2021 ◽

pp. 116376

Author(s):

Yichang Ren ◽

Yong Ruan ◽

Binbin Cheng ◽

Ling Li ◽

Jin Liu ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Quinoline Derivatives ◽

Anticancer Activities ◽

Design Synthesis ◽

3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.12.053 ◽

2019 ◽

Vol 168 ◽

pp. 426-435 ◽

Cited By ~ 14

Author(s):

Min'an Zhai ◽

Shiyuan Liu ◽

Meiqi Gao ◽

Long Wang ◽

Jun Sun ◽

...

Keyword(s):

Rational Design ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.1c00715 ◽

2021 ◽

Author(s):

Hao Chen ◽

Shanshan Deng ◽

Najah Albadari ◽

Mi-Kyung Yun ◽

Sicheng Zhang ◽

...

Keyword(s):

Binding Site ◽

Anticancer Agents ◽

Biological Evaluation ◽

Design Synthesis ◽

Tubulin Inhibitors ◽

Colchicine Binding Site ◽

Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site

Bioorganic Chemistry ◽

10.1016/j.bioorg.2018.12.015 ◽

2019 ◽

Vol 85 ◽

pp. 49-59 ◽

Cited By ~ 10

Author(s):

Wenlong Li ◽

Honghao Sun ◽

Feijie Xu ◽

Wen Shuai ◽

Jie Liu ◽

...

Keyword(s):

Binding Site ◽

Biological Evaluation ◽

Molecular Properties ◽

Tubulin Polymerization ◽

Vinyl Sulfone ◽

Colchicine Binding Site ◽

Molecular Properties Prediction ◽

Sulfone Derivatives

Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.111577 ◽

2019 ◽

Vol 181 ◽

pp. 111577 ◽

Cited By ~ 8

Author(s):

Romeo Romagnoli ◽

Paola Oliva ◽

Maria Kimatrai Salvador ◽

Maria Encarnacion Camacho ◽

Chiara Padroni ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Design, synthesis and biological evaluation of novel 5,6,7-trimethoxy-N-aryl-2-styrylquinolin-4-amines as potential anticancer agents and tubulin polymerization inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.103711 ◽

2020 ◽

Vol 98 ◽

pp. 103711 ◽

Cited By ~ 1

Author(s):

Salimeh Mirzaei ◽

Farhad Eisvand ◽

Farzin Hadizadeh ◽

Fatemeh Mosaffa ◽

Ali Ghasemi ◽

...

Keyword(s):

Anticancer Agents ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.9b00706 ◽

2019 ◽

Vol 62 (14) ◽

pp. 6734-6750 ◽

Cited By ~ 8

Author(s):

Qinghui Wang ◽

Kinsie E. Arnst ◽

Yuxi Wang ◽

Gyanendra Kumar ◽

Dejian Ma ◽

...

Keyword(s):

Binding Site ◽

Biological Evaluation ◽

Design Synthesis ◽

Colchicine Binding Site ◽

Design, synthesis and biological evaluation of novel indole-based oxalamide and aminoacetamide derivatives as tubulin polymerization inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2019.126816 ◽

2020 ◽

Vol 30 (2) ◽

pp. 126816 ◽

Cited By ~ 1

Author(s):

Peng-Cheng Diao ◽

Xie-Er Jian ◽

Peng Chen ◽

Chuan Huang ◽

Jie Yin ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽