3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.12.053 ◽

2019 ◽

Vol 168 ◽

pp. 426-435 ◽

Author(s):

Min'an Zhai ◽

Shiyuan Liu ◽

Meiqi Gao ◽

Long Wang ◽

Jun Sun ◽

...

Keyword(s):

Rational Design ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, Synthesis and Biological Evaluation of 1,4-Disubstituted-3,4-dihydroisoquinoline Compounds as New Tubulin Polymerization Inhibitors

International Journal of Molecular Sciences ◽

10.3390/ijms160510173 ◽

2015 ◽

Vol 16 (12) ◽

pp. 10173-10184 ◽

Author(s):

Ling Zhang ◽

Yunlong Song ◽

Jingjing Huang ◽

Jia Liu ◽

Wenwen Zhu ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, Synthesis and Biological Evaluation of Novel Acridine and Quinoline Derivatives as Tubulin Polymerization Inhibitors with Anticancer Activities

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2021.116376 ◽

2021 ◽

pp. 116376

Author(s):

Yichang Ren ◽

Yong Ruan ◽

Binbin Cheng ◽

Ling Li ◽

Jin Liu ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Quinoline Derivatives ◽

Anticancer Activities ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.111577 ◽

2019 ◽

Vol 181 ◽

pp. 111577 ◽

Author(s):

Romeo Romagnoli ◽

Paola Oliva ◽

Maria Kimatrai Salvador ◽

Maria Encarnacion Camacho ◽

Chiara Padroni ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel 5,6,7-trimethoxy-N-aryl-2-styrylquinolin-4-amines as potential anticancer agents and tubulin polymerization inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.103711 ◽

2020 ◽

Vol 98 ◽

pp. 103711 ◽

Author(s):

Salimeh Mirzaei ◽

Farhad Eisvand ◽

Farzin Hadizadeh ◽

Fatemeh Mosaffa ◽

Ali Ghasemi ◽

...

Keyword(s):

Anticancer Agents ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of resveratrol-cinnamoyl derivates as tubulin polymerization inhibitors targeting the colchicine binding site

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103319 ◽

2019 ◽

Vol 93 ◽

pp. 103319 ◽

Author(s):

Yong Yin ◽

Bao-Ping Lian ◽

Yuan-Zheng Xia ◽

Yu-Ying Shao ◽

Ling-Yi Kong

Keyword(s):

Binding Site ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Colchicine Binding Site ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel indole-based oxalamide and aminoacetamide derivatives as tubulin polymerization inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2019.126816 ◽

2020 ◽

Vol 30 (2) ◽

pp. 126816 ◽

Author(s):

Peng-Cheng Diao ◽

Xie-Er Jian ◽

Peng Chen ◽

Chuan Huang ◽

Jie Yin ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of 2-phenylquinoline-4-carboxamide derivatives as a new class of tubulin polymerization inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2017.09.004 ◽

2017 ◽

Vol 25 (21) ◽

pp. 5939-5951 ◽

Author(s):

Li Zhu ◽

Kaixiu Luo ◽

Ke Li ◽

Yi Jin ◽

Jun Lin

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

New Class ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, Synthesis and Biological Evaluation of Benz‐Fused Five‐Membered Heterocyclic Compounds as Tubulin Polymerization Inhibitors with Anticancer Activities

Chemical Biology & Drug Design ◽

10.1111/cbdd.13832 ◽

2021 ◽

Author(s):

Buduma Komuraiah ◽

Yichang Ren ◽

Mingming Xue ◽

Binbin Cheng ◽

Jin Liu ◽

...

Keyword(s):

Heterocyclic Compounds ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Anticancer Activities ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of (E)-3-(3,4-dihydroxyphenyl)acrylylpiperazine derivatives as a new class of tubulin polymerization inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2014.05.029 ◽

2014 ◽

Vol 22 (15) ◽

pp. 4285-4292 ◽

Author(s):

Yong Yin ◽

Fang Qiao ◽

Lu-Yi Jiang ◽

She-Feng Wang ◽

Shao Sha ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

New Class ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of 2,3‐diphenyl‐cycloalkyl pyrazole derivatives as potential tubulin polymerization inhibitors

Chemical Biology & Drug Design ◽

10.1111/cbdd.13565 ◽

2019 ◽

Vol 94 (5) ◽

pp. 1894-1904

Author(s):

Lin‐Ying Xia ◽

Rong Yang ◽

Ya‐Liang Zhang ◽

Yi‐Chun Chu ◽

Ya‐Lin Qi ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Pyrazole Derivatives ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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