Synthesis and antibacterial evaluation of (E)-1-(1H-indol-3-yl) ethanone O-benzyl oxime derivatives against MRSA and VRSA strains

2021 ◽  
pp. 105288
Author(s):  
Ravikumar Akunuri ◽  
Vaishnavi Veerareddy ◽  
Grace Kaul ◽  
Abdul Akhir ◽  
Tanveer Unnissa ◽  
...  
Keyword(s):  
Oxime Derivatives ◽  
Antibacterial Evaluation

Coupling of Steroid O-(Carboxymethyl)oxime Derivatives with Single-Protected α,ω-Diaminoalkanes

1999 ◽  
Vol 64 (12) ◽  
pp. 2035-2043 ◽  
Author(s):  
Vladimír Pouzar ◽  
Ivan Černý ◽  
Pavel Drašar
Keyword(s):  
Trifluoroacetic Acid ◽  
Protecting Groups ◽  
Oxime Group ◽  
Amino Groups ◽  
New Approach ◽  
Terminal Amino ◽  
Oxime Derivatives

New approach to the synthesis of steroid oximes bearing O-substituents with terminal amino groups was described. The easily accessible steroid O-(carboxymethyl)oximes were reacted with single-protected Boc-α,ω-diaminoalkanes to give corresponding amide intermediates. From them the Boc protecting groups were cleaved with trifluoroacetic acid to afford the desired steroid derivatives with terminal amino groups. The procedure was succesfully tested on steroids with O-(carboxymethyl)oxime group in positions 7 and 17. The decomposition of target products was observed during deprotection of substituted 19-oximes.

Isolation, structure elucidation, and antibacterial evaluation of the metabolites produced by the marine-sourced Streptomyces sp. ZZ820

Tetrahedron ◽  
2019 ◽  
Vol 75 (9) ◽  
pp. 1186-1193 ◽  
Author(s):  
Wenwen Yi ◽  
Qiao Li ◽  
Tengfei Song ◽  
Lei Chen ◽  
Xing-Cong Li ◽  
...  
Keyword(s):  
Structure Elucidation ◽  
Streptomyces Sp ◽  
Antibacterial Evaluation
Sign in / Sign up

Export Citation Format

Share Document