Isolation, structure elucidation, and antibacterial evaluation of the metabolites produced by the marine-sourced Streptomyces sp. ZZ820

Tetrahedron ◽  
2019 ◽  
Vol 75 (9) ◽  
pp. 1186-1193 ◽  
Author(s):  
Wenwen Yi ◽  
Qiao Li ◽  
Tengfei Song ◽  
Lei Chen ◽  
Xing-Cong Li ◽  
...  
2008 ◽  
Vol 63 (10) ◽  
pp. 1223-1230 ◽  
Author(s):  
Imran Sajid ◽  
Khaled A. Shaaban ◽  
Holm Frauendorf ◽  
Shahida Hasnain ◽  
Hartmut Laatscha

AbstractVal-Geninthiocin (2), a new member of thiopeptide antibiotics, was isolated from the mycelium of Streptomyces sp. RSF18, along with the closely related geninthiocin (1) and the macrolide, chalcomycin. By intensive NMR and MS studies, Val-geninthiocin (2) was identified as desoxygeninthiocin, a thiopeptide, containing several oxazole and thiazole units and a number of unusual amino acids. Compound 2 shows potent activity against Gram-positive bacteria and minor antifungal activity, while it is not effective against Gram-negative bacteria or microalgae. Here we describe the fermentation, isolation and structure elucidation as well as the biological activity of 2.


2019 ◽  
pp. 1-11
Author(s):  
Khaled A. Shaaban ◽  
Mohamed Shaaban ◽  
Marinus Meiners ◽  
Anja Schüffler ◽  
Gerhard Kelter ◽  
...  

ChemInform ◽  
2010 ◽  
Vol 31 (14) ◽  
pp. no-no
Author(s):  
Hitoshi Takeuchi ◽  
Naoki Asai ◽  
Kazunori Tanabe ◽  
Teruya Kozaki ◽  
Masanori Fujita ◽  
...  

1999 ◽  
Vol 52 (11) ◽  
pp. 971-982 ◽  
Author(s):  
HITOSHI TAKEUCHI ◽  
NAOKI ASAI ◽  
KAZUNORI TANABE ◽  
TERUYA KOZAKI ◽  
MASANORI FUJITA ◽  
...  

ChemInform ◽  
2001 ◽  
Vol 32 (12) ◽  
pp. no-no
Author(s):  
Nobuaki Naruse ◽  
Rena Kageyama-Kawase ◽  
Yasuhiro Funahashi ◽  
Toshiaki Wakabayashi ◽  
Yoshio Watanabe ◽  
...  

1998 ◽  
Vol 51 (3) ◽  
pp. 372-373 ◽  
Author(s):  
TETSUO AKIYAMA ◽  
RYUICHI SAWA ◽  
HIROSHI NAGANAWA ◽  
YASUHIKO MURAOKA ◽  
TAKAAKI AOYAGI ◽  
...  

2001 ◽  
Vol 54 (5) ◽  
pp. 434-440 ◽  
Author(s):  
ALEXANDRA HÖLTZEL ◽  
RALPH W. JACK ◽  
GRAEME J. NICHOLSON ◽  
GÜNTHER JUNG ◽  
KLAUS GEBHARDT ◽  
...  

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