Regulation of Editing and Expression of Glutamate α-Amino-Propionic-Acid (AMPA)/Kainate Receptors by Antidepressant Drugs

2006 ◽  
Vol 59 (8) ◽  
pp. 713-720 ◽  
Author(s):  
Alessandro Barbon ◽  
Maurizio Popoli ◽  
Luca La Via ◽  
Stefania Moraschi ◽  
Ivan Vallini ◽  
...  
Keyword(s):  
Propionic Acid ◽  
Antidepressant Drugs ◽  
Kainate Receptors ◽  
Amino Propionic Acid

Daboia russelli Venom Hyaluronidase: Purification, Characterization and Inhibition by β-3-(3-Hydroxy-4-Oxopyridyl) α-Amino-Propionic Acid

2011 ◽  
Vol 11 (20) ◽  
pp. 2556-2565 ◽  
Author(s):  
Y. H. Mahadeswaraswamy ◽  
B. Manjula ◽  
S. Devaraja ◽  
K. S. Girish ◽  
K. Kemparaju
Keyword(s):  
Propionic Acid ◽  
Amino Propionic Acid

scholarly journals Paradoxical Anti-Epileptic Effects of a GluR5 Agonist of Kainate Receptors

2002 ◽  
Vol 88 (1) ◽  
pp. 523-527 ◽  
Author(s):  
Ilgam Khalilov ◽  
June Hirsch ◽  
Rosa Cossart ◽  
Yehezkel Ben-Ari
Keyword(s):  
Propionic Acid ◽  
Therapeutic Approach ◽  
Hippocampal Neurons ◽  
Selective Excitation ◽  
Kainate Receptors ◽  
Kainate Receptor ◽  
Tert Butyl ◽  
Principal Cells ◽  
Selective Agonist

Kainate generates in adult hippocampal neurons a seizure but also a massive excitation of interneurons and a dramatic increase of the inhibitory drive that impinges on principal cells. This “overinhibition” is largely mediated by GluR5-containing kainate receptors that are enriched on interneurons. Here, using the neonatal intact hippocampus in vitro and the triple chamber, we first show that this mechanism is fully operative in neonatal neurons. We then report that application to one hippocampus of ( RS)-2-amino-3-(5-tert-butyl-3-hydroxy-4-isoxazolyl)propionic acid—a relatively selective agonist of GluR5 containing kainate receptors—depresses the propagation of seizure generated in the opposite hippocampus by a convulsive agent. We conclude that the selective excitation of interneurons by GluR5-containing kainate receptor agonists opens a new therapeutic approach for the epilepsies.

ChemInform Abstract: A Convenient Route to β-Amino Propionic Acid Derivatives.

ChemInform ◽  
2010 ◽  
Vol 30 (22) ◽  
pp. no-no
Author(s):  
Mrinal K. Kundu ◽  
Sujata V. Bhat
Keyword(s):  
Propionic Acid ◽  
Convenient Route ◽  
Amino Propionic Acid

Synthesis of Amino Propionic Acid Modified Polypropylene-Graft-Styrene Fiber

2014 ◽  
Vol 1033-1034 ◽  
pp. 420-423
Author(s):  
Yao Ran Sun ◽  
Shu De Duan ◽  
Rui Xia Guo ◽  
Rui Sheng Hu ◽  
Hai Li Yun
Keyword(s):  
Aqueous Solution ◽  
Propionic Acid ◽  
Ir Spectrum ◽  
Orthogonal Experiment ◽  
Experimental Results ◽  
Raw Material ◽  
Carboxyl Groups ◽  
Propanoic Acid ◽  
Reaction Conditions ◽  
Amino Propionic Acid

The amino propanoic acid chelating fiber (APACF) was prepared by immobilizing tetraethylenepentamine (TEPA) and propionic acid on polypropylene-graft-styrene (PP-g-ST). The synthetic conditions of amino PP-g-ST fiber and APACF were optimized by the way of L16(45) orthogonal experiment, and the optimizing reaction conditions were obtained. APACF was characterized by FTIR, and the changes of IR spectrum verified the introduction of carboxyl groups to the raw material. The experimental results revealed that the APACF can be used to remove and enrich copper from aqueous solution.

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