970. Binge Drinking Associated with Hippocampal Structural and Functional Abnormalities in Adults with a History of Childhood Adversity

2017 ◽  
Vol 81 (10) ◽  
pp. S392-S393
Author(s):  
Jonathan Ipser ◽  
Dan J. Stein ◽  
Hetta Gouse ◽  
Carla Freeman ◽  
John Joska
Keyword(s):  
Binge Drinking ◽  
Childhood Adversity ◽  
History Of Childhood ◽  
History Of

scholarly journals Rethinking childhood adversity in chronic fatigue syndrome

2015 ◽  
Author(s):  
James E Clark ◽  
Sean Davidson ◽  
Laura Maclachlan ◽  
Megan Lynn ◽  
Julia L Newton ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Childhood Trauma ◽  
Childhood Adversity ◽  
Chronic Fatigue ◽  
Childhood Trauma Questionnaire ◽  
History Of Childhood ◽  
Fatigue Syndrome ◽  
Increased Risk ◽  
Co Morbidity ◽  
History Of

Objectives: Previous studies have consistently shown increased rates of childhood adversity in chronic fatigue syndrome (CFS). However, such aetiopathogenic studies of CFS are potentially confounded by co-morbidity and misdiagnosis particularly with depression. We used a modelling approach with existing data and data generated in our examination of the rates of childhood adversity in a sample of CFS patients who had no lifetime history of depression. Methods: The childhood trauma questionnaire (CTQ) was completed by a sample of 52 participants and 19 controls with chronic fatigue syndrome who did not meet criteria for a psychiatric disorder (confirmed using the Structured Clinical Interview for DSM-IV). Subsequently, Mediation Analysis (Baye’s Rules) was used to establish the risk childhood adversity poses for CFS with and without depression. Results: In a cohort of CFS patients with depression robustly excluded, CTQ scores were markedly lower than in all previous studies and, in contrast to these previous studies, not increased compared with healthy controls. Post-hoc analysis showed that CTQ scores correlated with the number of depressive symptoms during the lifetime worst period of low mood. The probability of developing CFS given a history of childhood trauma was shown to be 4%, a two-fold increased risk compared to the general population. However, much of this risk is mediated by the concomitant development of major depression. Discussion: The data suggests that previous studies showing a relationship between childhood adversity and CFS may be mediated by depression

Preconception lifestyle intervention in obese infertile women is more effective for those with a history of childhood adversity

2019 ◽  
Vol 100 ◽  
pp. S10
Author(s):  
Lotte van Dammen ◽  
Nicole Bush ◽  
Susanne de Rooij ◽  
Cornelieke van de Beek ◽  
Henk Groen ◽  
...  
Keyword(s):  
Lifestyle Intervention ◽  
Childhood Adversity ◽  
History Of Childhood ◽  
Infertile Women ◽  
History Of

scholarly journals Blunted endocrine and cardiovascular reactivity in young healthy women reporting a history of childhood adversity

2015 ◽  
Vol 51 ◽  
pp. 58-67 ◽  
Author(s):  
Annette Voellmin ◽  
Katja Winzeler ◽  
Evelin Hug ◽  
Frank H. Wilhelm ◽  
Valérie Schaefer ◽  
...  
Keyword(s):  
Cardiovascular Reactivity ◽  
Childhood Adversity ◽  
History Of Childhood ◽  
Healthy Women ◽  
History Of

scholarly journals Rethinking childhood adversity in chronic fatigue syndrome

2015 ◽  
Author(s):  
James E Clark ◽  
Sean Davidson ◽  
Laura Maclachlan ◽  
Megan Lynn ◽  
Julia L Newton ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Childhood Trauma ◽  
Childhood Adversity ◽  
Chronic Fatigue ◽  
Childhood Trauma Questionnaire ◽  
History Of Childhood ◽  
Fatigue Syndrome ◽  
Increased Risk ◽  
Co Morbidity ◽  
History Of

Objectives: Previous studies have consistently shown increased rates of childhood adversity in chronic fatigue syndrome (CFS). However, such aetiopathogenic studies of CFS are potentially confounded by co-morbidity and misdiagnosis particularly with depression. We used a modelling approach with existing data and data generated in our examination of the rates of childhood adversity in a sample of CFS patients who had no lifetime history of depression. Methods: The childhood trauma questionnaire (CTQ) was completed by a sample of 52 participants and 19 controls with chronic fatigue syndrome who did not meet criteria for a psychiatric disorder (confirmed using the Structured Clinical Interview for DSM-IV). Subsequently, Mediation Analysis (Baye’s Rules) was used to establish the risk childhood adversity poses for CFS with and without depression. Results: In a cohort of CFS patients with depression robustly excluded, CTQ scores were markedly lower than in all previous studies and, in contrast to these previous studies, not increased compared with healthy controls. Post-hoc analysis showed that CTQ scores correlated with the number of depressive symptoms during the lifetime worst period of low mood. The probability of developing CFS given a history of childhood trauma was shown to be 4%, a two-fold increased risk compared to the general population. However, much of this risk is mediated by the concomitant development of major depression. Discussion: The data suggests that previous studies showing a relationship between childhood adversity and CFS may be mediated by depression

Miscellaneous Psychiatric Disorders

2021 ◽  
pp. 343-347
Author(s):  
Kari A. Martin
Keyword(s):  
Psychiatric Disorders ◽  
Social Stress ◽  
Psychological Symptoms ◽  
Medical Condition ◽  
Adult Population ◽  
Childhood Adversity ◽  
Care Utilization ◽  
History Of Childhood ◽  
History Of ◽  
High Level

In a number of psychiatric disorders, patients present with medical and psychological symptoms that are not well explained by a medical condition or substance use. The prevalence of somatic symptom disorder in the general US adult population may be about 5% to 7%. Associated demographic characteristics include female sex, older age, fewer years of education, lower socioeconomic status, unemployment, and a history of childhood adversity, comorbid psychiatric illness, social stress, and reinforcing illness benefits. A high level of medical care utilization rarely alleviates the patient’s concerns.

Sign in / Sign up

Export Citation Format

Share Document