scholarly journals Second generation of α-tocopherol analogs-nitric oxide donors: Synthesis, physicochemical, and biological characterization

2007 ◽  
Vol 15 (18) ◽  
pp. 6262-6272 ◽  
Author(s):  
Gloria V. López ◽  
Fabiana Blanco ◽  
Paola Hernández ◽  
Ana Ferreira ◽  
Oscar E. Piro ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Second Generation ◽  
Nitric Oxide Donors ◽  
Biological Characterization

P0111. Exogenous nitric oxide donors exhibit differential inhibition of NF-κB survival signaling dependent on strong vs. weak kinetic activators

Nitric Oxide ◽  
2006 ◽  
Vol 14 (4) ◽  
pp. 53
Author(s):  
Joseph A. Lupica ◽  
Joseph A. Bauer ◽  
Zhuo Tang ◽  
Daniel J. Lindner ◽  
Joseph A. DiDonato
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Donors ◽  
Differential Inhibition ◽  
Survival Signaling ◽  
Exogenous Nitric Oxide

Nitric oxide: a new role in intensive care

2020 ◽  
Vol 22 (1) ◽  
pp. 72-79
Author(s):  
Alexandra Lee ◽  
◽  
Warwick Butt ◽  
◽  
◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Potential Role ◽  
Nitric Oxide Donors ◽  
Ischaemia Reperfusion Injury ◽  
Surface Receptors ◽  
The Past ◽  
Ischaemia Reperfusion ◽  
Human Experiments ◽  
Endogenous Nitric Oxide

Inhaled nitric oxide has been used for 30 years to improve oxygenation and decrease pulmonary vascular resistance. In the past 15 years, there has been increased understanding of the role of endogenous nitric oxide on cell surface receptors, mitochondria, and intracellular processes involving calcium and superoxide radicals. This has led to several animal and human experiments revealing a potential role for administered nitric oxide or nitric oxide donors in patients with systemic inflammatory response syndrome or ischaemia–reperfusion injury, and in patients for whom exposure of blood to artificial surfaces has occurred.

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