Structure–activity relationships of substituted oxyoxalamides as inhibitors of the human soluble epoxide hydrolase

Quantitative Structure Activity Relationships Study of Soluble Epoxide Hydrolase Inhibitors Using MLR, ANN, CoMFA and CoMSIA Methods

ChemistrySelect ◽

10.1002/slct.201900471 ◽

2019 ◽

Vol 4 (20) ◽

pp. 6348-6353

Author(s):

Maryam Nazari ◽

Sayyed Abbas Tabatabai ◽

Elham Rezaee

Keyword(s):

Epoxide Hydrolase ◽

Quantitative Structure ◽

Quantitative Structure Activity Relationships

Structure Activity ◽

Soluble Epoxide Hydrolase Inhibitors ◽

Structure–activity relationships of amide–phosphonate derivatives as inhibitors of the human soluble epoxide hydrolase

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2015.10.016 ◽

2015 ◽

Vol 23 (22) ◽

pp. 7199-7210 ◽

Cited By ~ 10

Author(s):

In-Hae Kim ◽

Yong-Kyu Park ◽

Hisashi Nishiwaki ◽

Bruce D. Hammock ◽

Kosuke Nishi

Keyword(s):

Epoxide Hydrolase ◽

Structure−Activity Relationships of Cycloalkylamide Derivatives as Inhibitors of the Soluble Epoxide Hydrolase

10.1021/jm101431v ◽

2011 ◽

Vol 54 (6) ◽

pp. 1752-1761 ◽

Cited By ~ 12

Author(s):

In-Hae Kim ◽

Yong-Kyu Park ◽

Bruce D. Hammock ◽

Kosuke Nishi

Keyword(s):

Epoxide Hydrolase ◽

Structure–activity relationships of the plasminogen modulator SMTP with respect to the inhibition of soluble epoxide hydrolase

The Journal of Antibiotics ◽

10.1038/ja.2015.58 ◽

2015 ◽

Vol 68 (11) ◽

pp. 685-690 ◽

Cited By ~ 10

Author(s):

Naoki Matsumoto ◽

Eriko Suzuki ◽

Kota Tsujihara ◽

Yuuichi Nishimura ◽

Keiji Hasumi

Keyword(s):

Epoxide Hydrolase ◽

1-Aryl-3-(1-acylpiperidin-4-yl)urea Inhibitors of Human and Murine Soluble Epoxide Hydrolase: Structure−Activity Relationships, Pharmacokinetics, and Reduction of Inflammatory Pain

10.1021/jm100691c ◽

2010 ◽

Vol 53 (19) ◽

pp. 7067-7075 ◽

Cited By ~ 104

Author(s):

Tristan E. Rose ◽

Christophe Morisseau ◽

Jun-Yan Liu ◽

Bora Inceoglu ◽

Paul D. Jones ◽

...

Keyword(s):

Inflammatory Pain ◽

Epoxide Hydrolase ◽

Immunochemical quantitation of cytochrome P-450 isozymes and epoxide hydrolase in liver microsomes from polychlorinated or polybrominated biphenyl-treated rats. A study of structure-activity relationships.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)81991-7 ◽

1983 ◽

Vol 258 (9) ◽

pp. 5967-5976

Author(s):

A Parkinson ◽

S H Safe ◽

L W Robertson ◽

P E Thomas ◽

D E Ryan ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Liver Microsomes ◽

Structure Activity ◽

Immunochemical Quantitation ◽

Polybrominated Biphenyl ◽

Cytochrome P 450

Synthesis and Structure−Activity Relationship Studies of Urea-Containing Pyrazoles as Dual Inhibitors of Cyclooxygenase-2 and Soluble Epoxide Hydrolase

10.1021/jm2001376 ◽

2011 ◽

Vol 54 (8) ◽

pp. 3037-3050 ◽

Cited By ~ 99

Author(s):

Sung Hee Hwang ◽

Karen M. Wagner ◽

Christophe Morisseau ◽

Jun-Yan Liu ◽

Hua Dong ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Structure Activity Relationship ◽

Cyclooxygenase 2 ◽

Activity Relationship ◽

Structure Activity ◽

Dual Inhibitors

Further Exploration of the Structure-Activity Relationship of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2021.116507 ◽

2021 ◽

pp. 116507

Author(s):

Stephanie Wilt ◽

Sean Kodani ◽

Leah Valencia ◽

Paula K. Hudson ◽

Stephanie Sanchez ◽

...

Keyword(s):

Fatty Acid ◽

Epoxide Hydrolase ◽

Fatty Acid Amide Hydrolase ◽

Acid Amide ◽

Activity Relationship ◽

Structure Activity ◽

Amide Hydrolase ◽

Relationship Of ◽

Fatty Acid Amide

Synthesis and Structure–Activity Relationship Studies of Novel Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase

10.1021/jm301617j ◽

2013 ◽

Vol 56 (4) ◽

pp. 1777-1781 ◽

Cited By ~ 24

Author(s):

Karin Meirer ◽

Carmen B. Rödl ◽

Joanna M. Wisniewska ◽

Sven George ◽

Ann-Kathrin Häfner ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Dual Inhibitors

Insights into the structure of urea-like compounds as inhibitors of the juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm Manduca sexta: Analysis of the binding modes and structure–activity relationships of the inhibitors by docking and CoMFA calculations

Chemosphere ◽

10.1016/j.chemosphere.2010.11.048 ◽

2011 ◽

Vol 82 (11) ◽

pp. 1604-1613 ◽

Cited By ~ 17

Author(s):

Miguel Garriga ◽

Julio Caballero

Keyword(s):

Juvenile Hormone ◽

Manduca Sexta ◽

Epoxide Hydrolase ◽

Tobacco Hornworm ◽

Binding Modes ◽